Evidence map›Paper›PMID 31997818›Full record

ArticleNeural regeneration research2020

Lian Liu, Xiao-Yuan Sha, Yi-Ning Wu, Meng-Ting Chen, Jing-Xiang Zhong

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 59 citations in OpenAlex.

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  19. Pharmacokinetics and Excretion Study ofFoods (Basel, Switzerland) · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lian LiuDepartment of Ophthalmology, Affiliated First Hospital of Jinan University, Guangzhou, Guangdong Province, China.
Xiao-Yuan ShaDepartment of Ophthalmology, Affiliated First Hospital of Jinan University, Guangzhou, Guangdong Province, China.
Yi-Ning WuDepartment of Ophthalmology, Guangdong Women and Children Hospital, Guangzhou, Guangdong Province, China.
Meng-Ting ChenDepartment of Ophthalmology, Affiliated First Hospital of Jinan University, Guangzhou, Guangdong Province, China.
Jing-Xiang ZhongDepartment of Ophthalmology, Affiliated First Hospital of Jinan University, Guangzhou, Guangdong Province, China.
First Affiliated Hospital of Jinan University · CNGuangdong Province Women and Children Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulation of excessive reactive oxygen species can exacerbate any injury of retinal tissue because free radicals can trigger lipid peroxidation, protein damage and DNA fragmentation. Increased oxidative stress is associated with the common pathological process of many eye diseases, such as glaucoma, diabetic retinopathy and ischemic optic neuropathy. Many studies have demonstrated that Lycium barbarum polysaccharides (LBP) protects against oxidative injury in numerous cells and tissues. For the model of hypoxia we used cultured retinal ganglion cells and induced hypoxia by incubating with 200 µM cobalt chloride (CoCl

Indexed as

caspasecell apoptosiscobalt chlorideLycium barbarum polysaccharidesmitochondrial membrane potentialoxidative stress injuryreactive oxygen speciesretinal ganglion cells

Identifiers

PMID31997818
PMCPMC7059572
OpenAlexW3004364492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.