Evidence map›Paper›PMID 31997705›Full record

ArticleCirculation research2020

Identification of a Primary Renal AT

Brandon A Kemp, Nancy L Howell, John J Gildea, Susanna R Keller, Robert M Carey

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Effect of DCardiology discovery · 2023
    Article
  7. Article
  8. Review
  9. The Angiotensin ATPharmacological reviews · 2022
    Review
  10. Article
  11. Review
  12. Renal ATCirculation research · 2022
    Article
  13. The NaFrontiers in physiology · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Brandon A KempFrom the Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville (B.A.K., N.L.H., S.R.K., R.M.C.).
Nancy L HowellFrom the Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville (B.A.K., N.L.H., S.R.K., R.M.C.).
John J GildeaDepartment of Pathology, University of Virginia Health System, Charlottesville (J.J.G.).
Susanna R KellerFrom the Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville (B.A.K., N.L.H., S.R.K., R.M.C.).
Robert M CareyFrom the Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville (B.A.K., N.L.H., S.R.K., R.M.C.).
University of Virginia Health System · US

Funding

Renal AT2 Receptors in HypertensionR01HL128189 · NHLBI · UNIVERSITY OF VIRGINIA · PI KELLER, SUSANNA R · 2016 to 2024
$5.0M
NHLBI NIH HHS R01 HL128189
6 · The paper itself

Abstract

rationalePrevious studies identified a defect in Ang III (angiotensin III [des-aspartyl

objectiveThis study aimed to delineate in prehypertensive SHR kidneys the receptor or postreceptor defect causing impaired AT METHODS AND

resultsFemale 4-week-old Wistar Kyoto and SHR rats were studied after 24-hour systemic AT

conclusionsThe results demonstrate a primary renal proximal tubule cell AT

Indexed as

NatriuresisAngiotensin II Type 2 Receptor BlockersAnimalsCell Adhesion MoleculesCyclic GMPExtracellular FluidExtracellular Signal-Regulated MAP KinasesFemaleHypertensionKidney Tubules, ProximalMicrofilament ProteinsPhosphoproteinsPhosphorylationProtein TransportRatsRats, Inbred SHRAngiotensin II Type 2 Receptor BlockersCell Adhesion MoleculesCyclic GMPExtracellular Signal-Regulated MAP KinasesMicrofilament ProteinsPhosphoproteinsReceptor, Angiotensin, Type 2SodiumSodium-Hydrogen ExchangersSodium-Potassium-Exchanging ATPasesrc-Family KinasesVasodilator-Stimulated Phosphoproteinangiotensinhypertensionkidneynatriuresisrat

Identifiers

PMID31997705
PMCPMC7112539
OpenAlexW3004251041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.