Evidence map›Paper›PMID 31997625›Full record

ArticleYonsei medical journal2020

Core-Needle Biopsy Does Not Show Superior Diagnostic Performance to Fine-Needle Aspiration for Diagnosing Thyroid Nodules.

Ilah Shin, Eun Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Youngjean Park, Si Eun Lee, Hye Sun Lee, Jin Young Kwak

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ilah ShinDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2046-9426
Eun Kyung KimDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3368-5013
Hee Jung MoonDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5643-5885
Jung Hyun YoonDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2100-3513
Vivian Youngjean ParkDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5135-4058
Si Eun LeeDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3225-5484
Hye Sun LeeBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6328-6948
Jin Young KwakDepartment of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. docjin@yuhs.ac.ORCID https://orcid.org/0000-0002-6212-1495
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the diagnostic performances of fine-needle aspiration (FNA) and core-needle biopsy (CNB) for thyroid nodules according to nodule size. MATERIALS AND

methodsThis retrospective study included 320 thyroid nodules from 320 patients who underwent both FNA and CNB at outside clinics and proceeded with surgery in our institution between July 2012 and May 2019. According to nodule size, the diagnostic performances of FNA and CNB were calculated using various combinations of test-negatives and test-positives defined by the Bethesda categories and were compared using the generalized estimated equation and the Delong method.

resultsThere were 279 malignant nodules in 279 patients and 41 benign nodules in 41 patients. The diagnostic performance of FNA was mostly not different from CNB regardless of nodule size, except for negative predictive value, which was better for FNA than CNB when applying Criteria 1 and 2. When applying Criteria 3, the specificity and positive predictive value of FNA were superior to CNB regardless of size. When applying Criteria 4, diagnostic performance did not differ between FNA and CNB regardless of size. After applying Criteria 5, diagnostic performance did not differ between FNA and CNB in nodules ≥2 cm. However, in nodules ≥1 cm and all nodules, the sensitivity, accuracy, and negative predictive value of CNB were better than those of FNA.

conclusionCNB did not show superior diagnostic performance to FNA for diagnosing thyroid nodules.

Indexed as

AdultAgedBiopsy, Fine-NeedleBiopsy, Large-Core NeedleFemaleHumansMaleMiddle AgedRetrospective StudiesThyroid GlandThyroid NoduleYoung Adultbiopsy, fine-needlebiopsy, large-core needlethyroid neoplasmsUltrasonography

Identifiers

PMID31997625
PMCPMC6992459
OpenAlexW3004162434

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.