Evidence map›Paper›PMID 31997390›Full record

ArticleJournal of medical virology2020

Potential of large "first generation" human-to-human transmission of 2019-nCoV.

Xingguang Li, Junjie Zai, Xiaomei Wang, Yi Li

Abstract readComment
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. There is no "origin" to SARS-CoV-2.Environmental research · 2022
    Article
  14. [Androgenic status in men during COVID-19].Problemy endokrinologii · 2022
    Article
  15. Article
  16. Article
  17. Recent Chronology of COVID-19 Pandemic.Frontiers in public health · 2022
    Review
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Xingguang LiHubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan, China.ORCID 0000-0002-3470-2196
Junjie ZaiImmunology Innovation Team, School of Medicine, Ningbo University, Ningbo, China.
Xiaomei WangHubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan, China.
Yi LiHubei Engineering Research Center of Viral Vector, Wuhan University of Bioengineering, Wuhan, China.

Funding

K. C. Wong Magna Fund in Ningbo UniversityNational Natural Science Foundation of China 31470268
6 · The paper itself

Abstract

To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok, Thailand) were analyzed. Phylogenetic and likelihood-mapping analyses of these genome sequences were performed. On the basis of our results, the star-like signal and topology of 2019-nCoV may be indicative of potentially large "first generation" human-to-human virus transmission. We estimated that 2019-nCoV likely originated in Wuhan on 9 November 2019 (95% credible interval: 25 September 2019 and 19 December 2019), and that Wuhan is the major hub for the spread of the 2019-nCoV outbreak in China and elsewhere. Our results could be useful for designing effective prevention strategies for 2019-nCoV in China and beyond.

Indexed as

ChiropteraCoronavirusPneumoniaAnimalsBetacoronavirusChinaDisease OutbreaksHumansPhylogenySARS-CoV-2Thailand2019-nCoVBangkokoutbreakTMRCAWuhan

Identifiers

PMID31997390
PMCPMC7166825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.