Evidence map›Paper›PMID 31997372›Full record

ArticleStatistics in medicine2020

Profiling dialysis facilities for adverse recurrent events.

Jason P Estes, Yanjun Chen, Damla Şentürk, Connie M Rhee, Esra Kürüm, Amy S You, Elani Streja, Kamyar Kalantar-Zadeh, Danh V Nguyen

Abstract read
In one paragraph

Article in Statistics in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Health Care Provider Clustering Using Fusion Penalty in Quasi-Likelihood.Biometrical journal. Biometrische Zeitschrift · 2024
    Article
  3. Limitations of the Inter-Unit Reliability: A Set of Practical Examples.Health services & outcomes research methodology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Analysis of hospital readmissions with competing risks.Statistical methods in medical research · 2022
    Article
  9. MEASURING PERFORMANCE FOR END-OF-LIFE CARE.The annals of applied statistics · 2022
    Article
  10. Article
  11. Fixed Effects High-Dimensional Profiling Models in Low Information Context.International journal of statistics in medical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jason P EstesPratt & Whitney, East Hartford, Connecticut.ORCID 0000-0003-0639-1121
Yanjun ChenInstitute for Clinical and Translational Science, University of California, Irvine, California.
Damla ŞentürkDepartment of Biostatistics, University of California, Los Angeles, California.ORCID 0000-0002-7619-5428
Connie M RheeHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, California.
Esra KürümDepartment of Statistics, University of California, Riverside, California.ORCID 0000-0003-1767-1671
Amy S YouHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, California.
Elani StrejaHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, California.
Kamyar Kalantar-ZadehHarold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine School of Medicine, Orange, California.
Danh V NguyenDepartment of Medicine, University of California Irvine, Orange, California.ORCID 0000-0002-4025-8239

Funding

Multilevel Time-Dynamic Modeling of Hospitalization and Survival in Patients on DialysisR01DK092232 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURUM, ESRA, NGUYEN, DANH V · 2011 to 2025
$4.9M
Hypothyroidism, Cardiovascular Health, and Survival in Kidney DiseaseK23DK102903 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI RHEE, CONNIE MEEYOUNG · 2014 to 2018
$955k
NIDDK NIH HHS K23 DK102903NIDDK NIH HHS R01 DK092232
6 · The paper itself

Abstract

Profiling analysis aims to evaluate health care providers, such as hospitals, nursing homes, or dialysis facilities, with respect to a patient outcome. Previous profiling methods have considered binary outcomes, such as 30-day hospital readmission or mortality. For the unique population of dialysis patients, regular blood works are required to evaluate effectiveness of treatment and avoid adverse events, including dialysis inadequacy, imbalance mineral levels, and anemia among others. For example, anemic events (when hemoglobin levels exceed normative range) are recurrent and common for patients on dialysis. Thus, we propose high-dimensional Poisson and negative binomial regression models for rate/count outcomes and introduce a standardized event ratio measure to compare the event rate at a specific facility relative to a chosen normative standard, typically defined as an "average" national rate across all facilities. Our proposed estimation and inference procedures overcome the challenge of high-dimensional parameters for thousands of dialysis facilities. Also, we investigate how overdispersion affects inference in the context of profiling analysis. The proposed methods are illustrated with profiling dialysis facilities for recurrent anemia events.

Indexed as

Kidney Failure, ChronicRenal DialysisHospitalsHumansNursing HomesPatient Readmissionend-stage renal diseasefixed effectshigh-dimensional parametersnegative binomial regressionPoisson regressionprofiling analysis

Identifiers

PMID31997372
PMCPMC7125020

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.