Evidence map›Paper›PMID 31997083›Full record

Observational studyClinical rheumatology2020

Disease activity-based management of rheumatoid arthritis in Dutch daily clinical practice has improved over the past decade.

Marieke J Spijk-de Jonge, Julia M Weijers, Laura W M Boerboom, Anita M P Huis, Femke Atsma, Laura T C Van Hulst, Mart A F J van de Laar, Marlies E J L Hulscher, Piet L C M van Riel

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Marieke J Spijk-de Jonge *Radboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands.
Julia M Weijers *Radboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands. julia.weijers@radboudumc.nl.ORCID https://orcid.org/0000-0001-9756-9639
Laura W M Boerboom, Populierstraat 31, Oss, 5342 VA, The Netherlands.
Anita M P HuisRadboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands.
Femke AtsmaRadboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands.
Laura T C Van Hulst, Weezenhof 5204, Nijmegen, 6536 DZ, The Netherlands.
Mart A F J van de LaarDepartment of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.
Marlies E J L Hulscher *Radboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands.
Piet L C M van Riel *Radboud University Medical Center, Radboud Institute for Health Sciences, IQ Healthcare, PO box 9101 (114), 6500 HB, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLTuBerculosis Vaccine Initiative · NLUniversity of Twente · NL

Funding

AbbVie NA
6 · The paper itself

Abstract

To re-evaluate the adherence to clinical practice guidelines recommended disease activity-based management of rheumatoid arthritis (RA) in daily clinical practice, among Dutch rheumatologists in the past decade. In 2007, disease activity was measured in only 16% of outpatient visits. All rheumatologists that participated in the 2007 study were invited to re-enter our study in 2016/2017. If necessary, data were supplemented with data from other rheumatologists. For all 26 rheumatologists who agreed to participate in our study, data were collected from 30 consecutive patients that visited the outpatient clinic. Per patient, data from four consecutive rheumatologist outpatient visits were collected. Since 2007, disease activity was measured more frequently in Dutch daily clinical practice, increasing from 16 to 79% of visits (2440/3081 visits). In addition, intensification of medication based on disease activity scores increased from 33 to 50% of visits (260/525 visits). DAS/DAS28 was the most frequently used disease activity measure (1596/2440 visits). There was a wide variation among rheumatologists in measuring disease activity and intensification of medication, 20-100% and 0-75% respectively. Over the past years, there has been a large improvement in disease activity assessment in daily clinical practice. Disease activity-based medication intensifications, also called tight control or treat to target, increased to a lesser extent. Large variation between different rheumatologists and clinics indicates that there is still room for improvement. Key Points • Following guideline dissemination disease activity is assessed more frequently (79%). • There is large variation between rheumatologists, indicating room for improvement. • Finding factors that explain variation is necessary to improve tight control in daily practice.

Indexed as

Guideline AdherencePractice Guidelines as TopicAgedAntirheumatic AgentsArthritis, RheumatoidFemaleHumansMaleMiddle AgedNetherlandsPractice Patterns, Physicians'Remission InductionRetrospective StudiesRheumatologySeverity of Illness IndexSurveys and QuestionnairesAntirheumatic AgentsClinical practice guidelinesDisease activityRheumatoid arthritisTight controlVariation

Identifiers

PMID31997083
OpenAlexW3003771578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.