Evidence map›Paper›PMID 31997057›Full record

ArticleAIDS and behavior2020

Real-World Eligibility for HIV Pre-exposure Prophylaxis Among People Who Inject Drugs.

Jonathan Picard, Brendan Jacka, Stine Høj, Émélie Laverdière, Joseph Cox, Élise Roy, Julie Bruneau

Abstract read
In one paragraph

Article in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. HIV and Substance Use Disorders.Infectious disease clinics of North America · 2024
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan PicardResearch Center, Centre Hospitalier de L'Université de Montréal (CRCHUM), 900 rue Saint-Denis, Montréal, QC, H2X0A9, Canada.
Brendan JackaResearch Center, Centre Hospitalier de L'Université de Montréal (CRCHUM), 900 rue Saint-Denis, Montréal, QC, H2X0A9, Canada.
Stine HøjResearch Center, Centre Hospitalier de L'Université de Montréal (CRCHUM), 900 rue Saint-Denis, Montréal, QC, H2X0A9, Canada.
Émélie LaverdièreFaculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, Canada.
Joseph CoxDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Canada.
Élise RoyFaculty of Medicine and Health Sciences, Université de Sherbrooke, Longueuil, Canada.
Julie BruneauResearch Center, Centre Hospitalier de L'Université de Montréal (CRCHUM), 900 rue Saint-Denis, Montréal, QC, H2X0A9, Canada. julie.bruneau@umontreal.ca.

Funding

A Multi-site Multi-Setting RCT of Integrated HIV Prevention and HCV Care for PWIDR01DA045713 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRUNEAU, JULIE, FEASTER, DANIEL J · 2017 to 2022
$8.2M
CIHR MOP135260CIHR MOP210232Fonds de Recherche du Recherche - Santé FRSQ5227NIDA NIH HHS 1R01DA045713-01NIDA NIH HHS R01 DA045713
6 · The paper itself

Abstract

Recent studies have highlighted the efficacy of and willingness to use pre-exposure prophylaxis (PrEP) to prevent HIV infection among people who inject drugs (PWID), however knowledge of real-world applicability is limited. We aimed to quantify the real-world eligibility for HIV-PrEP among HIV-negative PWID in Montreal, Canada (n = 718). Eligibility was calculated according to US Centers for Disease Control and Prevention (CDC) guidelines and compared to risk of HIV acquisition according to the assessing the risk of contracting HIV (ARCH-IDU) risk screening tool. Over one-third of participants (37%) were eligible for HIV PrEP, with 1/3 of these eligible due to sexual risk alone. Half of participants were considered high risk of HIV acquisition according to ARCH-IDU, but there was poor agreement between the two measures. Although a large proportion of PWID were eligible for HIV-PrEP, better tools that are context- and location-informed are needed to identify PWID at higher risk of HIV acquisition.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisAnti-HIV AgentsCanadaHumansSubstance Abuse, IntravenousAnti-HIV AgentsHIV preventionMen who have sex with menPeople who inject drugsPre-exposure prophylaxisPrEP eligibility guidelines

Identifiers

PMID31997057
PMCPMC10710293

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.