Evidence map›Paper›PMID 31996846›Full record

ArticleNature2020

The molecular basis for sugar import in malaria parasites.

Abdul Aziz Qureshi, Albert Suades, Rei Matsuoka, Joseph Brock, Sarah E McComas, Emmanuel Nji, Laura Orellana, Magnus Claesson, Lucie Delemotte, David Drew

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
  2. A two-step mechanism for sugar translocation.Nature structural & molecular biology · 2026
    Article
  3. Determinants of metal import and specificity in a bacterial transporter.bioRxiv : the preprint server for biology · 2026
    Article
  4. Structural basis of glucose-6-phosphate transport by human SLC37A2.Nature structural & molecular biology · 2026
    Article
  5. Article
  6. Comparative analysis of STP6 and STP10 unravels molecular selectivity in sugar transport proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Structure and function ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. How Cryo-EM Has Expanded Our Understanding of Membrane Transporters.Drug metabolism and disposition: the biological fate of chemicals · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Abdul Aziz Qureshi *Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Albert Suades *Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Rei MatsuokaDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Joseph BrockDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Sarah E McComasDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Emmanuel NjiDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Laura OrellanaDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Magnus ClaessonDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Lucie DelemotteDepartment of Applied Physics, Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.
David DrewDepartment of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. ddrew@dbb.su.se.
Stockholm University · SEKTH Royal Institute of Technology · SEScience for Life Laboratory · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elucidating the mechanism of sugar import requires a molecular understanding of how transporters couple sugar binding and gating events. Whereas mammalian glucose transporters (GLUTs) are specialists

Indexed as

Allosteric RegulationAmino Acid MotifsAmino Acid SequenceBinding SitesBiological TransportCrystallography, X-RayGlucoseGlucose Transport Proteins, FacilitativeHumansMalariaModels, MolecularMonosaccharide Transport ProteinsPlasmodium falciparumProtein ConformationSubstrate SpecificitySugarsGlucoseGlucose Transport Proteins, FacilitativeMonosaccharide Transport ProteinsSugars

Identifiers

PMID31996846
OpenAlexW3003797627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.