ArticleScientific reports2020
Cell type, sub-region, and layer-specific speed representation in the hippocampal-entorhinal circuit.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Hippocampal Local Field Potentials Encode Continuous Flight Speed in Homing Pigeons via Complementary Gamma and Theta Signatures.Animals : an open access journal from MDPI · 2026Article
- Coordinating Cognition: The Entorhinal Cortex in Mnemonic, Temporal and Spatial Representation.Cells · 2026Review
- The dentate gyrus efficiently converges LEC and MEC inputs into multimodal, highly specific and reliable environmental representations.Nature neuroscience · 2026Article
- Aberrant medial entorhinal cortex dynamics link tau pathology to spatial memory impairment.bioRxiv : the preprint server for biology · 2026Article
- Spatial coding dysfunction and network instability in the aging medial entorhinal cortex.Nature communications · 2025Article
- Article
- Scaling of Ventral Hippocampal Activity during Anxiety.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Intrinsic Bipolar Head-Direction Cells in the Medial Entorhinal Cortex.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Resveratrol and Exercise Produce Recovered Ankle and Metatarsus Joint Movements after Penetrating Lesion in Hippocampus in Male Rats.Brain sciences · 2024Article
- A hippocampus-accumbens code guides goal-directed appetitive behavior.Nature communications · 2024Article
- Beyond Correlation: Optimal Transport Metrics For Characterizing Representational Stability and Remapping in Neurons Encoding Spatial Memory.bioRxiv : the preprint server for biology · 2023Article
- Dissecting cell-type-specific pathways in medial entorhinal cortical-hippocampal network for episodic memory.Journal of neurochemistry · 2023Review
- Inhibitory hippocampus-medial septum projection controls locomotion and exploratory behavior.Frontiers in synaptic neuroscience · 2023Article
- Beyond correlation: optimal transport metrics for characterizing representational stability and remapping in neurons encoding spatial memory.Frontiers in cellular neuroscience · 2023Article
- Article
- Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Combining Cortical Voltage Imaging and Hippocampal Electrophysiology for Investigating Global, Multi-Timescale Activity Interactions in the Brain.International journal of molecular sciences · 2022Article
- Microcircuits for spatial coding in the medial entorhinal cortex.Physiological reviews · 2022Review
- Supramammillary regulation of locomotion and hippocampal activity.Science (New York, N.Y.) · 2021Article
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3 authors.
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Abstract
It has been hypothesised that speed information, encoded by 'speed cells', is important for updating spatial representation in the hippocampus and entorhinal cortex to reflect ongoing self-movement during locomotion. However, systematic characterisation of speed representation is still lacking. In this study, we compared the speed representation of distinct cell types across sub-regions/layers in the dorsal hippocampus and medial entorhinal cortex of rats during exploration. Our results indicate that the preferred theta phases of individual neurons are correlated with positive/negative speed modulation and a temporal shift of speed representation in a sub-region/layer and cell type-dependent manner. Most speed cells located in entorhinal cortex layer 2 represented speed prospectively, whereas those in the CA1 and entorhinal cortex layers 3 and 5 represented speed retrospectively. In entorhinal cortex layer 2, putative CA1-projecting pyramidal cells, but not putative dentate gyrus/CA3-projecting stellate cells, represented speed prospectively. Among the hippocampal interneurons, approximately one-third of putative dendrite-targeting (somatostatin-expressing) interneurons, but only a negligible fraction of putative soma-targeting (parvalbumin-expressing) interneurons, showed negative speed modulation. Putative parvalbumin-expressing CA1 interneurons and somatostatin-expressing CA3 interneurons represented speed more retrospectively than parvalbumin-expressing CA3 interneurons. These findings indicate that speed representation in the hippocampal-entorhinal circuit is cell-type, pathway, and theta-phase dependent.
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