Evidence map›Paper›PMID 31996718›Full record

ArticleScientific reports2020

A Statistical Approach of Background Removal and Spectrum Identification for SERS Data.

Chuanqi Wang, Lifu Xiao, Chen Dai, Anh H Nguyen, Laurie E Littlepage, Zachary D Schultz, Jun Li

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chuanqi WangUniversity of Notre Dame, Department of Applied and Computational Mathematics and Statistics, Notre Dame, IN, 46556, United States.
Lifu XiaoThe Ohio State University, Department of Chemistry and Biochemistry, Columbus, OH, 43210, United States.
Chen DaiUniversity of Notre Dame, Department of Chemistry and Biochemistry, Notre Dame, IN, 46556, United States.
Anh H NguyenUniversity of Notre Dame, Department of Chemistry and Biochemistry, Notre Dame, IN, 46556, United States.
Laurie E LittlepageUniversity of Notre Dame, Department of Chemistry and Biochemistry, Notre Dame, IN, 46556, United States.
Zachary D SchultzThe Ohio State University, Department of Chemistry and Biochemistry, Columbus, OH, 43210, United States.
Jun LiUniversity of Notre Dame, Department of Applied and Computational Mathematics and Statistics, Notre Dame, IN, 46556, United States. jun.li@nd.edu.

Funding

Online Raman Diagnostics of OncometabolitesR33CA206922 · NCI · UNIVERSITY OF NOTRE DAME · PI SCHULTZ, ZACHARY · 2016 to 2018
$1.0M
NCI NIH HHS R33 CA206922
6 · The paper itself

Abstract

SERS (surface-enhanced Raman scattering) enhances the Raman signals, but the plasmonic effects are sensitive to the chemical environment and the coupling between nanoparticles, resulting in large and variable backgrounds, which make signal matching and analyte identification highly challenging. Removing background is essential, but existing methods either cannot fit the strong fluctuation of the SERS spectrum or do not consider the spectra's shape change across time. Here we present a new statistical approach named SABARSI that overcomes these difficulties by combining information from multiple spectra. Further, after efficiently removing the background, we have developed the first automatic method, as a part of SABARSI, for detecting signals of molecules and matching signals corresponding to identical molecules. The superior efficiency and reproducibility of SABARSI are shown on two types of experimental datasets.

Identifiers

PMID31996718
PMCPMC6989639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.