ArticleScientific reports2020
Facile One Pot Greener Synthesis of Sophorolipid Capped Gold Nanoparticles and its Antimicrobial Activity having Special Efficacy Against Gram Negative Vibrio cholerae.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 61 citations in OpenAlex.
- Metal nanoparticles as next-generation therapeutics against antimicrobial resistance: mechanisms, functionalization, and translational potential.Molecular biology reports · 2026Review
- Green-synthesized gold nanoparticles: as emerging tools to combat antimicrobial resistance and therapeutic applications in poultry.Veterinary research communications · 2026Review
- Sophorolipids: multifunctional microbial glycolipids with diverse bioactivities and applications.Biotechnology for biofuels and bioproducts · 2025Review
- Applications of Nanotechnology in Ruminant Animal Production: Advances, Challenges, and Future Prospects.Nanomaterials (Basel, Switzerland) · 2025Review
- Lactonic sophorolipids byRSC advances · 2025Article
- Facile Synthesis of Lecithin-Sophorolipid Liponiosomes Encapsulating SARS-CoV‑2 Proteins for Therapeutic Applications.ACS omega · 2025Article
- Valorization of oil refinery by-products: production of sophorolipids utilizing fatty acid distillates and their potential antibacterial, anti-biofilm, and antifungal activities.World journal of microbiology & biotechnology · 2024Article
- Use of nanotechnology-based nanomaterial as a substitute for antibiotics in monogastric animals.Heliyon · 2024Review
- Harnessing the Potential of Biosurfactants for Biomedical and Pharmaceutical Applications.Pharmaceutics · 2023Review
- Management and Mitigation of Vibriosis in Aquaculture: Nanoparticles as Promising Alternatives.International journal of molecular sciences · 2023Review
- The anti-inflammation and skin-moisturizing effects ofFrontiers in pharmacology · 2023Article
- Harnessing dual applications of a novel ascomycetes yeast,Frontiers in bioengineering and biotechnology · 2023Article
- Phase Behaviour, Functionality, and Physicochemical Characteristics of Glycolipid Surfactants of Microbial Origin.Frontiers in bioengineering and biotechnology · 2022Review
- Investigating cyanogen richRSC advances · 2021Article
- Nanotechnology-Based Delivery Systems for Antimicrobial Peptides.Pharmaceutics · 2021Review
- Green Synthesis of Metallic Nanoparticles Using Some Selected Medicinal Plants from Southern Africa and Their Biological Applications.Plants (Basel, Switzerland) · 2021Review
- Contributions of Glycolipid Biosurfactants and Glycolipid-Modified Materials to Antimicrobial Strategy: A Review.Pharmaceutics · 2021Review
- Deciphering the Antibacterial Role of Peptide FromFrontiers in microbiology · 2021Article
- Biosurfactants and anti-inflammatory activity: A potential new approach towards COVID-19.Current opinion in environmental science & health · 2020Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbes develop several strategies to survive in the adverse condition such as biofilm formation, attaining non-dividing state, altering drug target or drug, thereby increases the burden of drug dosage. To combat these issues, nanoparticles have shown an alternative approach for new treatment strategy but synthesis via chemical synthetic route limits their application in biomedical field. Here, green method for the synthesis of gold nanoparticles using sophorolipid (SL) is discussed that is characterized by various techniques. Initially, the antimicrobial activity was checked against metabolically active state of microbes; Gram-positive Staphylococcus aureus and Gram-negative Vibrio cholerae using XTT assay and growth kinetics assay. Results suggested higher efficacy of nanoparticles for Gram-negative, therefore further analyzed against Escherichia coli that confirmed its potency for the same. AuNPs-SL also signifies its efficiency at least metabolically active state; non dividing cells and biofilm of these microbes. Induced morphological changes were studied by SEM that revealed AuNPs-SL led to disruption of cell membrane and leakage of intracellular fluid to the surroundings. Inhibition of respiratory enzymes activity also plays a crucial role in bactericidal action as indicated by LDH assay. Synergy of AuNPs-SL with different antibiotics was also analyzed using checkerboard assay. These results suggested the possible use of AuNPs-SL as an antimicrobial therapy in the field of nanomedicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.