Evidence map›Paper›PMID 31996604›Full record

ArticleThe Journal of head trauma rehabilitation

Physical and Functional Impairment Among Older Adults With a History of Traumatic Brain Injury.

Erica S Kornblith, Kenneth M Langa, Kristine Yaffe, Raquel C Gardner

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 3 countries.

Erica S KornblithSan Francisco Veterans Affairs Medical Center, San Francisco, California (Drs Kornblith, Yaffe, and Gardner); Division of General Medicine, University of Michigan Health System, Ann Arbor (Dr Langa); Veterans Affairs Center for Practice Management and Outcomes Research, Washington, District of Columbia (Dr Langa); Institute for Social Research, University of Michigan, Ann Arbor (Dr Langa); Institute of Gerontology, University of Michigan, Ann Arbor (Dr Langa); Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor (Dr Langa); and Departments of Neurology (Drs Yaffe and Gardner) and Psychiatry & Epidemiology & Biostatistics (Dr Yaffe), University of California San Francisco (UCSF).
Kenneth M Langa
Kristine Yaffe
Raquel C Gardner
Mount Wachusett Community College · US

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Michigan Alzheimer's Disease Core CenterP30AG053760 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIEBERMAN, ANDREW P · 2016 to 2020
$10.1M
Dementia Prevalence over Time: Proximate Causes and ConsequencesR01AG053972 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 2016 to 2021
$4.9M
Predictors & Outcomes of Cognitive Trajectories in the Oldest OldK24AG031155 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YAFFE, KRISTINE · 2007 to 2020
$1.5M
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical TrajectoriesK23NS095755 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARDNER, RAQUEL C. · 2015 to 2019
$872k
Intramural VA VA999999NIA NIH HHS K24 AG031155NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG053760NIA NIH HHS R01 AG053972NIA NIH HHS U01 AG009740NINDS NIH HHS K23 NS095755
6 · The paper itself

Abstract

objectivesTo examine the association of lifetime history of traumatic brain injury (TBI) with later-life physical impairment (PI) and functional impairment (FI) and to evaluate the impact of neurobehavioral symptoms that frequently co-occur with TBI on these relations.

participantsA total of 1148 respondents to the 2014 Wave of the Health and Retirement Study, a nationally representative survey of older community-dwelling adults, randomly selected to participate in a TBI exposure survey. They reported no prior TBI (n = 737) or prior TBI (n = 411).

designCross-sectional survey study. MAIN MEASURES: Physical impairment (self-reported difficulty with ≥1 of 8 physical activities); FI (self-reported difficulty with ≥1 of 11 activities of daily living); self-reported current neurobehavioral symptoms (pain, sleep problems, depression, subjective memory impairment); The Ohio State University TBI Identification Method (OSU-TBI-ID)-short form. ANALYSES: Stepwise logistic regression models ([1] unadjusted; [2] adjusted for demographics and medical comorbidities; [3] additionally adjusted for neurobehavioral symptoms) compared PI and FI between TBI groups.

resultsTraumatic brain injury-exposed (mean: 33.6 years postinjury) respondents were younger, less likely to be female, and reported more comorbidities and neurobehavioral symptoms. Although TBI was significantly associated with increased odds of PI and FI in unadjusted models and models adjusted for demographics/comorbidities (adjusted odds ratio, 95% confidence interval: PI 1.62, 1.21-2.17; FI 1.60, 1.20-2.14), this association was no longer statistically significant after further adjustment for neurobehavioral symptoms.

conclusionHistory of TBI is associated with substantial PI and FI among community-dwelling older adults. Further research is warranted to determine whether aggressive management of neurobehavioral symptoms in this population may mitigate long-term PI and FI in this population.

Indexed as

Activities of Daily LivingBrain Injuries, TraumaticAgedCross-Sectional StudiesFemaleHumansIndependent LivingMaleMiddle AgedOdds RatioPhysical Functional PerformancePsychomotor Disorders

Identifiers

PMID31996604
PMCPMC7335322
OpenAlexW3003316963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.