Evidence map›Paper›PMID 31996462›Full record

ArticleScience translational medicine2020

Immune correlates of tuberculosis disease and risk translate across species.

Mushtaq Ahmed, Shyamala Thirunavukkarasu, Bruce A Rosa, Kimberly A Thomas, Shibali Das, Javier Rangel-Moreno, Lan Lu, Smriti Mehra, Stanley Kimbung Mbandi, Larissa B Thackray and 8 more

Open access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Therapeutic remodeling of the tuberculosis granuloma with 1-methyl-D-tryptophan enhances CD8Proceedings of the National Academy of Sciences of the United States of America · 2026
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  17. Systems analysis reveals alternate metabolic states adopted bybioRxiv : the preprint server for biology · 2025
    Article
  18. Article
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  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Mushtaq AhmedDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-6296-7626
Shyamala ThirunavukkarasuDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0001-9888-3304
Bruce A RosaMcDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-6820-446X
Kimberly A ThomasDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0001-8152-9974
Shibali DasDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0003-1263-8178
Javier Rangel-MorenoDepartment of Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY 14624, USA.
Lan LuDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Smriti MehraDepartment of Microbiology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.
Stanley Kimbung MbandiSouth African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-6121-9039
Larissa B ThackrayDepartment of Medicine, Division of Infectious Diseases, Washington University in St. Louis, St. Louis, MO 63110, USA.
Michael S DiamondDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
Kenneth M MurphyDepartment of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.ORCID 0000-0002-3505-9630
Terry MeansAutoimmunity Cluster, Immunology & Inflammation Therapeutic Area, Sanofi, Cambridge, MA 02139, USA.ORCID 0000-0001-7622-0462
John MartinMcDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63110, USA.
Deepak KaushalSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245, USA.ORCID 0000-0003-3521-1257
Thomas J ScribaSouth African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-0641-1359
Makedonka MitrevaMcDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63110, USA. sakhader@wustl.edu mmitreva@wustl.edu.ORCID 0000-0001-9572-3436
Shabaana A KhaderDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA. sakhader@wustl.edu mmitreva@wustl.edu.ORCID 0000-0002-9545-4982
Washington University in St. Louis · USJames S. McDonnell Foundation · USUniversity of Cape Town · ZAInflammation Research Foundation · USTexas Biomedical Research Institute · USTulane University · USUniversity of Rochester Medical Center · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Viral Testing CoreU42OD010442 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Deepak Kaushal, Kathryn Shelton · 2012 to 2026
$35.6M
Systems Biology Identifies Restriction Factors for West Nile VirusU19AI106772 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WATERS, KATRINA M. · 2013 to 2017
$26.1M
Universiity of Rochester Center for Medical Countermeasures against RadiationU19AI091036 · NIAID · UNIVERSITY OF ROCHESTER · PI CHEN, YUHCHYAU · 2010 to 2014
$15.6M
ROLE OF INDUCIBLE BRONCHUS ASSOCIATED LYMPHOID TISSUE IN LATENT TUBERCULOSISR01AI111914 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2015 to 2025
$11.1M
ROLE OF IL-17 IN PROTECTIVE VACCINE-INDUCED IMMUNE RESPONSES AGAINST TUBERCULOSISR01HL105427 · NHLBI · WASHINGTON UNIVERSITY · PI KHADER, SHABAANA A. · 2011 to 2025
$5.9M
The Role of Group 3 Innate Lymphoid cells (ILC3) in TuberculosisR01AI134236 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, KHADER, SHABAANA A. · 2017 to 2021
$4.4M
Perturbation of antigen-specific T cell responses in latent TB/SIV co-infectionR01AI111943 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KAUSHAL, DEEPAK, RENGARAJAN, JYOTHI · 2015 to 2019
$3.9M
COMMON IMMUNE CORRELATES OF RISK OF TB DISEASE IN ANIMAL MODELS AND HUMANSR01AI123780 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2016 to 2019
$2.9M
NHLBI NIH HHS R01 HL105427NIAID NIH HHS R01 AI111914NIAID NIH HHS R01 AI111943NIAID NIH HHS R01 AI123780NIAID NIH HHS R01 AI134236NIAID NIH HHS U19 AI091036NIAID NIH HHS U19 AI106772NIH HHS P51 OD011104NIH HHS P51 OD011133NIH HHS U42 OD010442
6 · The paper itself

Abstract

One quarter of the world's population is infected with

Indexed as

AnimalsDisease Models, AnimalDisease ProgressionGene Expression ProfilingHumansImmunityMacacaMice, Inbred C57BLRisk FactorsSpecies SpecificityTuberculosis

Identifiers

PMID31996462
PMCPMC7354419
OpenAlexW3003268933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.