Evidence map›Paper›PMID 31996440›Full record

ArticleJournal of clinical microbiology2020

Evaluation of the NG-Test MCR-1 Lateral Flow Assay and EDTA-Colistin Broth Disk Elution Methods To Detect Plasmid-Mediated Colistin Resistance among Gram-Negative Bacterial Isolates.

Alexander J Fenwick, Yehudit Bergman, Shawna Lewis, Rebecca Yee, Anne-Catrin Uhlemann, Nicolynn Cole, Peggy Kohner, Carly Ordak, Daniel A Green, Audrey N Schuetz and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Adaptive colistin resistance dynamics inMicrobiology spectrum · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. The Clash of the Titans: COVID-19, Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Alexander J FenwickDivision of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yehudit BergmanDivision of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Shawna LewisDivision of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rebecca YeeDivision of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Anne-Catrin UhlemannDivision of Infectious Diseases, Columbia University Irving Medical Center, New York, New York, USA.
Nicolynn ColeDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Peggy KohnerDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Carly OrdakEnvironmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Daniel A GreenClinical Microbiology Laboratory, Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0002-2394-1319
Audrey N SchuetzDivision of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Romney HumphriesAccelerate Diagnostics, Tucson, Arizona, USA.
Patricia J SimnerDivision of Medical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA psimner1@jhmi.edu.
Johns Hopkins University · USMayo Clinic · USColumbia University Irving Medical Center · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmid-mediated colistin resistance (PMCR) is a global public health concern, given its ease of transmissibility. The purpose of this study was to evaluate two methods for the detection of PMCR from bacterial colonies: (i) the NG-Test MCR-1 lateral flow immunoassay (LFA; NG Biotech, Guipry, France) and (ii) the EDTA-colistin broth disk elution (EDTA-CBDE) screening test method. These methods were evaluated using a cohort of contemporary, clinical Gram-negative bacillus isolates from 3 U.S. academic medical centers (126 isolates of the

Indexed as

Anti-Bacterial AgentsColistinDrug Resistance, BacterialEdetic AcidFranceHumansMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsColistinEdetic AcidcolistinMCRmethodsplasmid-mediated

Identifiers

PMID31996440
PMCPMC7098752
OpenAlexW3001083068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.