Evidence map›Paper›PMID 31996420›Full record

ArticlemSphere2020

Toxoplasma gondii Dysregulates Barrier Function and Mechanotransduction Signaling in Human Endothelial Cells.

Armond L Franklin-Murray, Sharmila Mallya, Allen Jankeel, Suhas Sureshchandra, Ilhem Messaoudi, Melissa B Lodoen

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Human Brain Endothelial Cell-Derived Extracellular Vesicles ReduceInternational journal of molecular sciences · 2025
    Article
  4. iScience · 2024
    Article
  5. Article
  6. Construction and biological function ofZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  7. Review
  8. Modeling the human placental barrier to understandFrontiers in cellular and infection microbiology · 2023
    Review
  9. Review
  10. Review
  11. The Chlamydia trachomatis Tarp effector targets the Hippo pathway.Biochemical and biophysical research communications · 2021
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Armond L Franklin-MurrayDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Sharmila MallyaDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Allen JankeelDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Suhas SureshchandraDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Ilhem MessaoudiDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA.
Melissa B LodoenDepartment of Molecular Biology & Biochemistry, University of California, Irvine, California, USA mlodoen@uci.edu.
University of California, Irvine · US

Funding

Dysregulation of maternal immunity during pregnancy by pregravid obesityR01AI145910 · NIAID · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM · 2019 to 2024
$3.4M
Maternal obesity and neonatal innate immunityR01AI142841 · NIAID · UNIVERSITY OF KENTUCKY · PI MESSAOUDI, ILHEM, VARLAMOV, OLEG · 2018 to 2024
$2.7M
Parasite dissemination in Toxoplasmic encephalitisR01AI120846 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LODOEN, MELISSA BRUCKNER · 2016 to 2020
$2.0M
Parasite dissemination in Toxoplasmic encephalitisR56AI120846 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LODOEN, MELISSA BRUCKNER · 2015 to 2015
$386k
NIAID NIH HHS R01 AI120846NIAID NIH HHS R01 AI142841NIAID NIH HHS R01 AI145910NIAID NIH HHS R56 AI120846
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Membrane PermeabilityMechanotransduction, CellularActinsAdaptor Proteins, Signal TransducingAntigens, CDbeta CateninCadherin 5CadherinsCell PolarityCells, CulturedCytoskeletonHippo Signaling PathwayHumansHuman Umbilical Vein Endothelial CellsProtein Serine-Threonine KinasesRNA-SeqActinsAdaptor Proteins, Signal TransducingAntigens, CDbeta CateninCadherin 5CadherinsCTNNB1 protein, humanLATS1 protein, humanProtein Serine-Threonine KinasesTranscription FactorsYAP1 protein, humanYAP-Signaling Proteinsactinendothelial cellHippo signalingmechanotransductionToxoplasma gondiiVE-cadherin

Identifiers

PMID31996420
PMCPMC6992369
OpenAlexW3003721121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.