Evidence map›Paper›PMID 31996415›Full record

ArticlemSphere2020

Mouse Genetic Background Affects Transfer of an Antibiotic Resistance Plasmid in the Gastrointestinal Tract.

Logan C Ott, Zachary R Stromberg, Graham A J Redweik, Michael J Wannemuehler, Melha Mellata

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. A defined microbiota mouse model forFrontiers in microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Dietary zinc supplementation inhibits bacterial plasmid conjugationApplied and environmental microbiology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Antibiotics (Basel, Switzerland) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. mSphere · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Logan C Ott *Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0002-6464-9840
Zachary R Stromberg *Department of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.
Graham A J RedweikDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.ORCID https://orcid.org/0000-0002-5201-0134
Michael J WannemuehlerDepartment of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, Iowa, USA.
Melha MellataDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA mmellata@iastate.edu.ORCID https://orcid.org/0000-0002-4967-7173
Iowa State University · US

Funding

Highly simplified model of a mammalian intestinal communityR01GM099537 · NIGMS · IOWA STATE UNIVERSITY · PI PHILLIPS, JAMES GREGORY · 2013 to 2016
$1.0M
NIGMS NIH HHS R01 GM099537
6 · The paper itself

Abstract

Dissemination of antibiotic resistance (AR) genes, often on plasmids, leads to antibiotic-resistant bacterial infections, which is a major problem for animal and public health. Bacterial conjugation is the primary route of AR gene transfer in the mammalian gastrointestinal tract. Significant gaps in knowledge about which gastrointestinal communities and host factors promote plasmid transfer remain. Here, we used

Indexed as

Gastrointestinal MicrobiomeAnimalsDrug Resistance, BacterialEscherichia coliFemaleGene Transfer, HorizontalIntestinesMaleMiceMice, 129 StrainMice, Inbred C3HMice, KnockoutPlasmidsSalmonella entericaaltered Schaedler floraantibiotic resistancegut microbiotahorizontal gene transferplasmid

Identifiers

PMID31996415
PMCPMC6992376
OpenAlexW3003230501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.