Evidence map›Paper›PMID 31996373›Full record

ArticleThe Journal of biological chemistry2020

A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing

Michael L Hayes, Paola I Santibanez

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 87 citations in OpenAlex.

  1. A rapid and efficient in planta assay for assessment of RNA editing factor performance.The Plant journal : for cell and molecular biology · 2026
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  4. RNA-Binding Proteins in Dinoflagellates.International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael L HayesDepartment of Chemistry and Biochemistry, California State University Los Angeles, Los Angeles, California 90032. Electronic address: mhayes3@calstatela.edu.
Paola I SantibanezDepartment of Chemistry and Biochemistry, California State University Los Angeles, Los Angeles, California 90032.
California State University Los Angeles · US

Funding

Research Initiative for Scientific Enhancement (RISE)R25GM061331 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI FOSTER, KRISHNA L · 2000 to 2021
$33.1M
The Role of Zinc ions for RNA Binding and Catalytic Function of the DYW-deaminaseSC2GM122718 · NIGMS · CALIFORNIA STATE UNIVERSITY LOS ANGELES · PI HAYES, MICHAEL LLOYD · 2017 to 2019
$438k
NIGMS NIH HHS R25 GM061331NIGMS NIH HHS SC2 GM122718
6 · The paper itself

Abstract

Pentatricopeptide repeat (PPR) proteins with C-terminal DYW domains are present in organisms that undergo C-to-U editing of organelle RNA transcripts. PPR domains act as specificity factors through electrostatic interactions between a pair of polar residues and the nitrogenous bases of an RNA target. DYW-deaminase domains act as the editing enzyme. Two moss (

Indexed as

BiocatalysisRepetitive Sequences, Amino AcidAdenosine TriphosphateBryopsidaCytidineCytosineIonsMagnesiumMutationPlant ExtractsPlant ProteinsProtein AggregatesProtein DomainsProtein MultimerizationRecombinant ProteinsRNA EditingAdenosine TriphosphateCytidineCytosineIonsMagnesiumPlant ExtractsPlant ProteinsProtein Aggregatespyrimidin-2-one beta-ribofuranosideRecombinant ProteinsTetrahydrouridineUracilZincC-to-U editingdeaminaseDYW domainmetal ion-protein interactionmetalloenzymemitochondriaorganellepentatricopeptide repeat (PPR)PPR65RNA editing

Identifiers

PMID31996373
PMCPMC7076202
OpenAlexW3003217570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.