Evidence map›Paper›PMID 31996247›Full record

ArticleMolecular brain2020

TRPC1 mediates slow excitatory synaptic transmission in hippocampal oriens/alveus interneurons.

André Kougioumoutzakis, Joe Guillaume Pelletier, Isabel Laplante, Abdessattar Khlaifia, Jean-Claude Lacaille

Open access · goldAbstract read
In one paragraph

Article in Molecular brain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. How TRPC Channels Modulate Hippocampal Function.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

André KougioumoutzakisDepartment of Neurosciences and GRSNC, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, Montreal, QC, H3C 3J7, Canada.
Joe Guillaume PelletierDepartment of Neurosciences and GRSNC, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, Montreal, QC, H3C 3J7, Canada.
Isabel LaplanteDepartment of Neurosciences and GRSNC, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, Montreal, QC, H3C 3J7, Canada.
Abdessattar KhlaifiaDepartment of Neurosciences and GRSNC, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, Montreal, QC, H3C 3J7, Canada.
Jean-Claude LacailleDepartment of Neurosciences and GRSNC, Université de Montréal, P.O. Box 6128, Station Downtown, Montreal, Montreal, QC, H3C 3J7, Canada. jean-claude.lacaille@umontreal.ca.ORCID 0000-0003-4056-0574
Université de Montréal · CA

Funding

CIHR PJT-153311
6 · The paper itself

Abstract

Hippocampal GABAergic interneurons play key roles in regulating principal cell activity and plasticity. Interneurons located in stratum oriens/alveus (O/A INs) receive excitatory inputs from CA1 pyramidal cells and express a Hebbian form of long-term potentiation (LTP) at their excitatory input synapses. This LTP requires the activation of metabotropic glutamate receptors 1a (mGluR1a) and Ca

Indexed as

AnimalsBacterial ProteinsBiolisticsCA1 Region, HippocampalExcitatory Postsynaptic PotentialsGenes, ReporterHEK293 CellsHumansInterneuronsLong-Term PotentiationLuminescent ProteinsMultiplex Polymerase Chain ReactionNerve Tissue ProteinsOrgan Culture TechniquesPatch-Clamp TechniquesProtein Interaction MappingBacterial ProteinsLuminescent Proteinsmetabotropic glutamate receptor type 1Nerve Tissue ProteinsReceptors, Metabotropic GlutamateRNA, Small Interferingtransient receptor potential cation channel, subfamily C, member 1TRPC4 ion channelTRPC Cation Channelsyellow fluorescent protein, BacteriaGABA interneuronsHippocampusmGluR1a-mediated slow EPSCsiRNATRPC subtypes

Identifiers

PMID31996247
PMCPMC6988362
OpenAlexW3007311030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.