Evidence map›Paper›PMID 31996209›Full record

Trial reportMalaria journal2020

Effect of group versus individual antenatal care on uptake of intermittent prophylactic treatment of malaria in pregnancy and related malaria outcomes in Nigeria and Kenya: analysis of data from a pragmatic cluster randomized trial.

Lisa Noguchi, Lindsay Grenier, Mark Kabue, Emmanuel Ugwa, Jaiyeola Oyetunji, Stephanie Suhowatsky, Brenda Onguti, Bright Orji, Lillian Whiting-Collins, Oniyire Adetiloye

Open access · goldAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Malaria journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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  5. Impact of group prenatal care on key prenatal services and educational topics in Malawi and Tanzania.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Lisa NoguchiJhpiego, 1615 Thames Street, Baltimore, MD, 21231, USA. lisa.noguchi@jhpiego.org.ORCID http://orcid.org/0000-0002-3119-0324
Lindsay GrenierJhpiego, 1615 Thames Street, Baltimore, MD, 21231, USA.
Mark KabueJhpiego, 1615 Thames Street, Baltimore, MD, 21231, USA.
Emmanuel UgwaJhpiego Nigeria, Plot 971 Reuben Okoya Crescent, Utako, Abuja, Nigeria.
Jaiyeola OyetunjiJhpiego Nigeria, Plot 971 Reuben Okoya Crescent, Utako, Abuja, Nigeria.
Stephanie SuhowatskyJhpiego, 1615 Thames Street, Baltimore, MD, 21231, USA.
Brenda OngutiJhpiego Kenya, Ring Road, 14 Riverside, Nairobi, Kenya.
Bright OrjiJhpiego Nigeria, Plot 971 Reuben Okoya Crescent, Utako, Abuja, Nigeria.
Lillian Whiting-CollinsJohns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD, 21205, USA.
Oniyire AdetiloyeJhpiego Nigeria, Plot 971 Reuben Okoya Crescent, Utako, Abuja, Nigeria.
Johns Hopkins University · USNational Institute of Child Health · PK

Funding

Bill and Melinda Gates Foundation OPP1134962
6 · The paper itself

Abstract

backgroundEvery year, malaria in pregnancy contributes to approximately 20% of stillbirths in sub-Saharan Africa and 10,000 maternal deaths globally. Most eligible pregnant women do not receive the minimum three recommended doses of intermittent preventive treatment with Sulfadoxine-pyrimethamine (IPTp-SP). The objective of this analysis was to determine whether women randomized to group antenatal care (G-ANC) versus standard antenatal care (ANC) differed in IPTp uptake and insecticide-treated nets (ITN) use.

methodsProspective data were analysed from the G-ANC study, a pragmatic, cluster randomized, controlled trial that investigated the impact of G-ANC on various maternal newborn health-related outcomes. Data on IPTp were collected via record abstraction and difference between study arms in mean number of doses was calculated by t test for each country. Data on ITN use were collected via postpartum interview, and difference between arms calculated using two-sample test for proportions.

resultsData from 1075 women and 419 women from Nigeria and Kenya, respectively, were analysed: 535 (49.8%) received G-ANC and 540 (50.2%) received individual ANC in Nigeria; 211 (50.4%) received G-ANC and 208 (49.6%) received individual ANC in Kenya. Mean number of IPTp doses received was higher for intervention versus control arm in Nigeria (3.45 versus 2.14, p < 0.001) and Kenya (3.81 versus 2.72, p < 0.001). Reported use of ITN the previous night was similarly high in both arms for mothers in Nigeria and Kenya (over 92%). Reported ITN use for infants was higher in the intervention versus control arm in Nigeria (82.7% versus 75.8%, p = 0.020).

conclusionsG-ANC may support better IPTp-SP uptake, possibly related to better ANC retention. However, further research is needed to understand impact on ITN use. Trial registration Pan African Clinical Trials Registry, May 2, 2017 (PACTR201706002254227).

Indexed as

AdolescentAdultAntimalarialsCluster AnalysisCohort StudiesDrug CombinationsFemaleHumansInfantInfant, NewbornInsecticide-Treated BednetsKenyaMalariaNigeriaPregnancyPregnancy Complications, ParasiticAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineAntenatal careGroup antenatal careInsecticide-treated netMalariaPregnancyPrenatal careSulfadoxine–pyrimethamine

Identifiers

PMID31996209
PMCPMC6990503
OpenAlexW3003482470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.