Evidence map›Paper›PMID 31996202›Full record

ArticleBMC surgery2020

Comparison of score-based prediction of 90-day mortality after liver resection.

Tanja Knoblich, Ulf Hinz, Christos Stravodimos, Michael R Schön, Arianeb Mehrabi, Markus W Büchler, Katrin Hoffmann

Abstract read
In one paragraph

Article in BMC surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanja KnoblichDepartment of General, Visceral and Transplant Surgery, Ruprecht-Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Ulf HinzDepartment of General, Visceral and Transplant Surgery, Ruprecht-Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Christos StravodimosDepartment of General and Visceral Surgery, Städtisches Klinikum, Moltkestraße 90, 76133, Karlsruhe, Germany.
Michael R SchönDepartment of General and Visceral Surgery, Städtisches Klinikum, Moltkestraße 90, 76133, Karlsruhe, Germany.
Arianeb MehrabiDepartment of General, Visceral and Transplant Surgery, Ruprecht-Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Markus W BüchlerDepartment of General, Visceral and Transplant Surgery, Ruprecht-Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.
Katrin HoffmannDepartment of General, Visceral and Transplant Surgery, Ruprecht-Karls University, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. katrin.hoffmann@med.uni-heidelberg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndications for liver surgery are expanding fast and complexity of procedures increases. Preoperative mortality risk assessment by scoring systems is debatable. A previously published externally validated Mortality Risk Score allowed easy applicable and precise prediction of postoperative mortality. Aim of the study was to compare the performance of the Mortality Risk Score with the standard scores MELD and P-POSSUM.

methodsData of 529 patients undergoing liver resection were analysed. Mortality Risk Score, the labMELD Score and the P-POSSUM Scores (PS, OS, P-POSSUM mortality %) were calculated. The ROC curves of the three scoring systems were computed and the areas under the curve (C-index) were calculated using logistic regression models. Comparisons between the ROC curves were performed using the corresponding Wald tests.

resultsInternal validation confirmed that the risk model was predictive for a 90-day mortality rate with a C-index of 0.8421. The labMELD Score had a C-index of 0.7352 and the P-POSSUM system 0.6795 (PS 0.6953, OS 0.5413). The 90-day mortality rate increased with increasing labMELD values (p < 0.0001). Categorized according to the Mortality Risk Score Groups the labMELD Score showed a linear increase while the POSSUM Scores showed variable results.

conclusionsBy accurately predicting the risk of postoperative mortality after liver surgery the Mortality Risk Score should be useful at the selection stage. Prediction can be adjusted by use of the well-established labMELD Score. In contrast, the performance of standard P-POSSUM Scores is limited.

Indexed as

AgedFemaleHepatectomyHumansLiverMaleMiddle AgedPostoperative PeriodRisk AssessmentROC CurveSeverity of Illness IndexLiver resectionMortalityPrognostic score

Identifiers

PMID31996202
PMCPMC6990529

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.