ArticleBMC cancer2020
Superiority of NBI endoscopy to PET/CT scan in detecting esophageal cancer among head and neck cancer patients: a retrospective cohort analysis.
Article in BMC cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Prevalence of lung tumors in patients with esophageal squamous cell carcinoma and vice versa: a systematic review and meta-analysis.Journal of cancer research and clinical oncology · 2023Pooled it
- Factors associated with the development of second primary tumours in head and neck cancer patients.European journal of cancer care · 2022Pooled it
- Endoscopic screening of the upper gastrointestinal tract for second primary tumors in patients with head and neck cancer in a Western country.Endoscopy · 2023Trial
- Endoscopic iso-pathlength self-calibration for direction-resolved retrieval of tissue optical properties.Journal of biomedical optics · 2026Article
- Prior Cancer and Survival in Patients With Esophageal Squamous Cell Carcinoma.JAMA network open · 2026Article
- Updated evidence on the accuracy ofQuantitative imaging in medicine and surgery · 2026Review
- Utilizing Narrow Band Imaging for Early Detection of Recurrence in Follow-Up Patients with Head and Neck Squamous Cell Carcinoma Treated with Curative Intent Using Radiotherapy/Chemo-Radiotherapy: Enhancing Detection and Patient Outcomes.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Evaluation of a multimodal ctDNA-based assay for detection of aggressive cancers lacking standard screening tests.Future oncology (London, England) · 2025Article
- Article
- Effect of anesthesia assistance on the detection rate of precancerous lesions and early esophageal squamous cell cancer in esophagogastroduodenoscopy screening: A retrospective study based on propensity score matching.Frontiers in medicine · 2023Article
- Screening for head and neck tumors in patients with esophageal squamous cell carcinoma and vice versa: a nationwide survey among medical specialists.Endoscopy international open · 2022Article
- Endoscopic Screening for Second Primary Tumors of the Esophagus Among Head and Neck Cancer Patients.Frontiers in oncology · 2022Review
- The diagnostic significance of 64-slice spiral CT combined with serological CA19-9, Bcl-2, CYFRA21-1 detection in thoracic esophageal carcinoma.Translational cancer research · 2021Article
- Screening for synchronous esophageal second primary tumors in patients with head and neck cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Article
- Current state of prognostication, therapy and prospective innovations for Barrett's-related esophageal adenocarcinoma: a literature review.Journal of gastrointestinal oncology · 2021Review
- Correlation between microvessel density (MVD) and multi-spiral CT (MSCT) perfusion parameters of esophageal cancer lesions and the diagnostic value of combined CtBP2 and P16Journal of gastrointestinal oncology · 2021Article
- Article
- Laryngeal and Hypopharyngeal Malignancies: Where Do We Stand? A Retrospective Single-center Study.In vivo (Athens, Greece)Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSecond primary cancer of the esophagus is frequent in head and neck patients, especially in high-risk populations, and has a great impact on the prognosis. Although Positron emission tomography (PET)/computed tomography (CT) scan is commonly conducted in head and neck patients, its ability to detect early esophageal cancer is limited. Narrow-band imaging endoscopy is an accurate and convenient technique for esophageal examination. We aimed to compare PET/CT scan and narrow-band imaging endoscopy for the detection of esophageal cancer in head and neck cancer patients.
methodsFrom November 2015 to November 2018, all head and neck cancer patients who underwent both PET/CT scan and narrow-band imaging endoscopy at Changhua Christian Hospital were retrospectively enrolled. Descriptive statistics, receiver operating characteristic curve analysis, logistic regression analysis, independent Student's t-test, and Kaplan-Meier survival analysis were conducted with MedCalc Statistical Software.
resultsA total of 147 subjects were included in the analysis; suspicious esophageal lesions were identified by PET/CT scan in 8 (5.44%) and by narrow-band imaging in 35 (23.81%). The final pathologic diagnoses were esophageal squamous cell carcinoma in 10 and high-grade dysplasia in 5. The respective sensitivity, specificity, and area under the curve for detecting suspicious esophageal lesions were 33.33, 97.73%, and 0.655 for PET/CT scan, and 100.0, 84.85%, and 0.924 for narrow-band imaging endoscopy. Hypopharyngeal or laryngeal location of the primary head and neck cancer was the only risk factor for developing second primary esophageal cancer.
conclusionsPET/CT scan was inferior to narrow-band imaging endoscopy in detecting second primary esophageal cancer in head and neck cancer patients. In addition to PET/CT scan, narrow-band imaging endoscopy should be considered in head and neck patients at high risk for developing second primary esophageal cancer.
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