Evidence map›Paper›PMID 31996166›Full record

Trial reportBMC psychiatry2020

Cognitive testing of the PHQ-9 for depression screening among pregnant and postpartum women in Kenya.

Jennifer Velloza, John Njoroge, Kenneth Ngure, Nicholas Thuo, Catherine Kiptinness, Richard Momanyi, Snaidah Ayub, Stephen Gakuo, Nelly Mugo, Jane Simoni and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jennifer VellozaDepartment of Global Health, University of Washington, Seattle, USA. jvelloza@uw.edu.ORCID 0000-0001-7242-7415
John NjorogePartners in Health and Research Development, Nairobi, Kenya.
Kenneth NgureDepartment of Community Health Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Nicholas ThuoPartners in Health and Research Development, Nairobi, Kenya.
Catherine KiptinnessPartners in Health and Research Development, Nairobi, Kenya.
Richard MomanyiPartners in Health and Research Development, Nairobi, Kenya.
Snaidah AyubPartners in Health and Research Development, Nairobi, Kenya.
Stephen GakuoPartners in Health and Research Development, Nairobi, Kenya.
Nelly MugoDepartment of Global Health, University of Washington, Seattle, USA.
Jane SimoniDepartment of Global Health, University of Washington, Seattle, USA.
Renee HeffronDepartment of Global Health, University of Washington, Seattle, USA.
Partners for Health and Development in Africa · KEUniversity of Washington · USJomo Kenyatta University of Agriculture and Technology · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Antiretroviral periconception HIV prevention for HIV discordant couplesR00HD076679 · NICHD · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2015 to 2017
$742k
Enhancing safer conception for HIV serodiscordant couples through mobile technologiesR21TW009908 · FIC · UNIVERSITY OF WASHINGTON · PI HEFFRON, RENEE A. · 2014 to 2015
$349k
Depression and Pre-Exposure Prophylaxis Use among sub-Saharan African WomenF31MH113420 · NIMH · UNIVERSITY OF WASHINGTON · PI VELLOZA, JENNIFER · 2017 to 2018
$84k
FIC NIH HHS R21 TW009908NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI007140NICHD NIH HHS R00 HD076679NIMH NIH HHS F31 MH113420
6 · The paper itself

Abstract

backgroundAfrican women face high rates of depression, particularly during pregnancy or postpartum or after a recent HIV diagnosis. The Patient Health Questionnaire-9 (PHQ-9) depression screening tool has been quantitatively validated and extensively used to identify depression and link individuals to care. However, qualitative work is necessary to identify important opportunities to improve PHQ-9 question comprehension and performance among Kenyan women.

methodsWe administered the Kiswahili or English PHQ-9 (based on preference) to 29 pregnant and postpartum women in Thika, Kenya. Following administration, we conducted cognitive interviews with a purposive sample of 20 women. We used analytic memos and data matrices to identify themes around scale acceptability, comprehension, and decision and response processes.

resultsMost participants preferred to answer the PHQ-9 in Kiswahili (N = 15; 52%). Among the 20 interview participants, 12 (60%) had scores ≥5, indicating depressive symptoms. Overall, participants found the scale acceptable as an interviewer-administered tool. Participants reported few problems related to comprehension but had difficulty answering items not relevant to their lives (e.g., "watching television") and double-barreled items (e.g., "poor appetite or overeating"). They were hesitant to endorse items related to "duties as a wife and mother" and suicidal ideation. Most participants had difficulty distinguishing between response options of "several days" and "more than half the days".

conclusionsWe detected several problems related to PHQ-9 comprehension, decision processes, and response processes. We provide recommended changes to instructions and item wording to improve PHQ-9 validity among Kenyan women.

Indexed as

AdultDepression, PostpartumFemaleHIV InfectionsHumansKenyaMass ScreeningMental Status and Dementia TestsMothersPatient Health QuestionnairePilot ProjectsPostpartum PeriodPregnancyPregnancy ComplicationsReproducibility of ResultsSuicidal IdeationDepressionKenyaPHQ-9PregnancyWomen

Identifiers

PMID31996166
PMCPMC6990517
OpenAlexW3004865002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.