Evidence map›Paper›PMID 31996071›Full record

ArticleAutophagy2020

A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells.

Miao-Qing Zhang, Qiong Zhao, Jing-Pu Zhang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Miao-Qing ZhangKey Laboratory of Biotechnology of Antibiotics, the National Health Commission (NHC), Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, China.
Qiong ZhaoKey Laboratory of Biotechnology of Antibiotics, the National Health Commission (NHC), Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, China.
Jing-Pu ZhangKey Laboratory of Biotechnology of Antibiotics, the National Health Commission (NHC), Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing, China.
National Health and Family Planning Commission · CNChina Resources (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IFNL2 is a potent antiviral interferon, but the regulation of its gene expression is not fully clear. Here, we report the regulation of ATG10S for

Indexed as

Transcription, GeneticAmino Acid MotifsAutophagy-Related ProteinsBase SequenceBinding SitesCell NucleusGreen Fluorescent ProteinsHep G2 CellsHumansInterferon LambdaInterferon Regulatory Factor-1InterleukinsModels, BiologicalPromoter Regions, GeneticProtein BindingProtein DomainsATG10 protein, humanAutophagy-Related ProteinsGreen Fluorescent ProteinsInterferon Lambdainterferon-lambda, humanInterferon Regulatory Factor-1InterleukinsIRF1 protein, humanProtein IsoformsTranscription FactorsVesicular Transport ProteinsATG10Score motiffunctional nucleotidesIFNL2 promoterIFNL2 transcriptionIRF1

Identifiers

PMID31996071
PMCPMC7751675
OpenAlexW3003912257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.