Evidence map›Paper›PMID 31995337›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie2020

The economic impact of periprosthetic infection in total hip arthroplasty

Jason Akindolire, Mina W. Morcos, Jacquelyn D. Marsh, James L. Howard, Brent A. Lanting, Edward M. Vasarhelyi

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05932823 completednot on this map

Airflow and Hip Prosthesis Infections: A Registry Study Comparing Laminar vs. Turbulent Flow in the Danish Hip Arthroplasty Register.

Typeobservational_patient_registrySponsorUniversity Hospital Bispebjerg and FrederiksbergRan2010 to 2021Enrolled110,000ConditionsHip Prosthesis InfectionArmsLaminary airflow
NCT06798168 availablenot on this map

Bacteriophage Clinical Trial for Periprosthetic Joint Infection of Multidrug Resistant Pseudomonas Aeruginosa

Typeexpanded_accessSponsorOttawa Hospital Research InstituteConditionsJoint InfectionArmsCombining bacteriophage therapy with antibiotics for a case with hip PJI
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Jason AkindolireFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
Mina W. MorcosFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
Jacquelyn D. MarshFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
James L. HowardFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
Brent A. LantingFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
Edward M. VasarhelyiFrom the Division of Orthopaedic Surgery, Department of Surgery, Western University, London, Ont. (Akindolire, Morcos, Marsh, Howard, Lanting, Vasarhelyi); and the Division of Orthopaedic Surgery, London Health Sciences Centre, London, Ont. (Akindolire, Morcos, Howard, Lanting, Vasarhelyi).
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periprosthetic joint infection (PJI) is the third leading cause of total hip arthroplasty (THA) failure. Although controversial, 2-stage revision remains the gold standard treatment for PJI in most situations. To date, there have been few studies describing the economic impact of PJI in today’s health care environment. The purpose of the current study was to obtain an accurate estimate of the institutional cost associated with the management of PJI in THA and to assess the economic burden of PJI compared with primary uncomplicated THA. Methods: We conducted a review of primary THA cases and 2-stage revision THA for PJI at our institution. Patients were matched for age and body mass index. All costs associated with each procedure were recorded. Descriptive statistics were used to summarize the collected data. Mean costs, length of stay, clinic visits and readmission rates associated with the 2 cohorts were compared. Results: Fifty consecutive cases of revision THA were matched with 50 cases of uncomplicated primary THA between 2006 and 2014. Compared with the primary THA cohort, PJI was associated with a significant increase in mean length of hospital stay (26.5 v. 2.0 d, p < 0.001), mean number of clinic visits (9.2 v. 3.8, p < 0.001), number of readmissions (12 v. 1, p < 0.001) and average overall cost (Can$38 107 v. Can$6764, t = 8.3, p < 0.001). Conclusion: Treatment of PJI is a tremendous economic burden. Our data suggest a 5-fold increase in hospital expenditure in the management of PJI compared with primary uncomplicated THA.

Indexed as

Cost of IllnessArthroplasty, Replacement, HipHospital CostsHumansProsthesis FailureProsthesis-Related InfectionsRetrospective Studies

Identifiers

PMID31995337
PMCPMC7828941
OpenAlexW2559657889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.