Evidence map›Paper›PMID 31995274›Full record

ArticleESC heart failure2020

Prescription patterns of diabetes medications influencing clinical outcomes of heart failure patients with reduced ejection fraction.

Hung-Yu Chang, Yu-Wen Su, An-Ning Feng, Man-Cai Fong, Kuan-Chih Huang, Eric Chong, Kuan-Chun Chen, Wei-Hsian Yin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hung-Yu ChangHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
Yu-Wen SuFaculty of Medicine, School of Medicine, National Yang Ming University, Taipei, Taiwan.
An-Ning FengHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
Man-Cai FongHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
Kuan-Chih HuangHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
Eric ChongDivision of Cardiology, Farrer Park Hospital, Singapore, Singapore.
Kuan-Chun ChenHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
Wei-Hsian YinHeart Center, Cheng Hsin General Hospital, No. 45, Cheng-Hsin Street, 112 Beitou, Taipei, Taiwan.
National Taipei University · TWCheng Hsin General Hospital · TWNational Defense Medical Center · TWNational Yang Ming University Hospital · TWSingapore Science Park · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe collected the different prescription patterns of diabetes medications in a cohort of patients with heart failure with reduced ejection fraction (HFrEF) and analysed the impact of different prescription patterns on clinical outcomes. METHODS AND

resultsConsecutive diabetic patients with HFrEF from a heart failure referral centre were retrospectively analysed between 2015 and 2016. Exclusion criteria include being lost to follow-up, not receiving diabetes medications, and having severe renal impairment with a glomerular filtration rate < 30 mL/min/1.73 m

conclusionsPrescription patterns of diabetes medications in diabetics with HFrEF were diverse among different specialists. Prescriptions of metformin and SGLT2i were associated with favourable clinical outcomes. Our finding indicates the importance of awareness of beneficial effect of different classes of diabetes medications and collaboration between specialists in the management of diabetic HFrEF patients.

Indexed as

Diabetes MellitusHeart FailureAgedFemaleHumansMaleMiddle AgedPrescriptionsRetrospective StudiesStroke VolumeVentricular Function, LeftDiabetes mellitusHeart failureMetforminSodium-glucose co-transporter 2 inhibitor (SGLT2i)

Identifiers

PMID31995274
PMCPMC7160466
OpenAlexW3003376002

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.