Evidence map›Paper›PMID 31995262›Full record

Trial reportEuropean eating disorders review : the journal of the Eating Disorders Association2020

Family-based treatment for adolescent anorexia nervosa: What happens to rates of comorbid diagnoses?

Claire Trainor, Sasha Gorrell, Elizabeth K Hughes, Susan M Sawyer, Claire Burton, Daniel Le Grange

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in European eating disorders review : the journal of the Eating Disorders Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Psychotropic medication use in treatment-seeking youth with eating disorders.European eating disorders review : the journal of the Eating Disorders Association · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Claire TrainorDepartment of Psychiatry, University of California, San Francisco, CA.ORCID 0000-0002-8342-7362
Sasha GorrellDepartment of Psychiatry, University of California, San Francisco, CA.
Elizabeth K HughesThe University of Melbourne, Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Australia.ORCID 0000-0002-4377-5610
Susan M SawyerThe University of Melbourne, Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Australia.
Claire BurtonThe University of Melbourne, Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, Australia.
Daniel Le GrangeDepartment of Psychiatry, University of California, San Francisco, CA.

Funding

CLINICAL SERVICES RESEARCH TRAINING PROGRAMT32MH018261 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kaja Zabrina LeWinn, Rachel L. Loewy · 1985 to 2026
$7.0M
2/2 Predictors and Course of Postpartum Obsessions and CompulsionsR01MH118261 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 2019 to 2023
$2.1M
Baker FoundationBaker Foundation (Australia)NIMH NIH HHS R01 MH118261NIMH NIH HHS T32 MH018261Victorian Government
6 · The paper itself

Abstract

objectiveRates of psychiatric comorbidity are elevated in adolescents with anorexia nervosa, but little is known about how psychiatric comorbidity changes following family-based treatment (FBT).

methodsAdolescents with anorexia nervosa (N = 107) enrolled in a randomized controlled trial comparing two forms of FBT completed the Mini International Neuropsychiatric Interview for Children and Adolescents at baseline and end of treatment. Analyses tested whether baseline comorbid diagnoses predicted the presence of comorbid diagnoses at end of treatment and if baseline eating disorder psychopathology impacted this association.

resultsRates of comorbid diagnoses decreased from 54% at baseline to 26% at end of treatment. Logistic regression analyses indicated that individuals with multiple comorbid diagnoses at baseline were more likely to meet criteria for a comorbid condition at end of treatment (b = 2.00, p < .05). Individuals with reported psychotropic medication use were less likely to meet criteria for a comorbid condition at end of treatment (b = -1.63, p = .04). Diagnostic rates for major depressive disorder, generalized anxiety disorder, and panic disorder/agoraphobia decreased following FBT.

conclusionsFindings suggest that FBT for adolescent anorexia nervosa may aid in the resolution of some co-occurring psychiatric diagnoses. Continued research is needed to understand factors contributing to comorbid symptom improvement throughout treatment.

Indexed as

Family TherapyAdolescentAnorexia NervosaComorbidityFemaleHumansMaleMental DisordersPsychiatric Status Rating Scalesadolescentsanorexia nervosafamily-based treatmentpsychiatric comorbidityrecovery

Identifiers

PMID31995262
PMCPMC7192783

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.