Evidence map›Paper›PMID 31995253›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2020

Ovariectomy Activates Chronic Low-Grade Inflammation Mediated by Memory T Cells, Which Promotes Osteoporosis in Mice.

Anna Cline-Smith, Ariel Axelbaum, Elena Shashkova, Mousumi Chakraborty, Jessie Sanford, Prabhjyot Panesar, Macey Peterson, Linda Cox, Angel Baldan, Deborah Veis and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. General View of Arachidonic Acid (AA) Metabolism.Reviews of physiology, biochemistry and pharmacology · 2027
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anna Cline-SmithDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Ariel AxelbaumDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Elena ShashkovaDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Mousumi ChakrabortyDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Jessie SanfordDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Prabhjyot PanesarDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Macey PetersonDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Linda CoxDivision of Bone and Mineral Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Angel BaldanDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Deborah VeisDivision of Bone and Mineral Diseases, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.ORCID 0000-0001-7101-5582
Rajeev AuroraDepartment of Molecular Microbiology & Immunology, Saint Louis University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-6609-6055
Saint Louis University · USWashington University in St. Louis · US

Funding

Resource Based Center for Musculoskeletal Biology and Medicine (Overall Application)P30AR074992 · NIAMS · WASHINGTON UNIVERSITY · PI MATTHEW J SILVA · 2019 to 2026
$6.8M
The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI SILVA, MATTHEW J · 2009 to 2018
$5.7M
Control Sterol and Lipoprotein Homeostasis by miRNAR01HL107794 · NHLBI · SAINT LOUIS UNIVERSITY · PI BALDAN, ANGEL · 2011 to 2019
$3.3M
A Negative Feedback Loop Between Osteoclasts and CD8 T-CellsR01AR064821 · NIAMS · SAINT LOUIS UNIVERSITY · PI AURORA, RAJEEV · 2014 to 2018
$1.7M
High Throughput Screening to Identify Small Molecule Rank AgonistsR01AR068438 · NIAMS · SAINT LOUIS UNIVERSITY · PI GRIGGS, DAVID · 2015 to 2017
$1.0M
NHLBI NIH HHS R01 HL107794NIAMS NIH HHS P30 AR057235NIAMS NIH HHS P30 AR074992NIAMS NIH HHS R01 AR064821NIAMS NIH HHS R01 AR068438
6 · The paper itself

Abstract

The loss of estrogen (E

Indexed as

Immunologic MemoryOsteoporosisAnimalsFemaleHumansInflammationMiceOvariectomyT-Lymphocytes

Identifiers

PMID31995253
PMCPMC8061311
OpenAlexW3003921069

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.