Evidence map›Paper›PMID 31995029›Full record

ArticleeLife2020

Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance.

Andrés Aranda-Díaz, Benjamin Obadia, Ren Dodge, Tani Thomsen, Zachary F Hallberg, Zehra Tüzün Güvener, William B Ludington, Kerwyn Casey Huang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 80 citations in OpenAlex.

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  19. Antibiotic perturbations to the gut microbiome.Nature reviews. Microbiology · 2023
    Review
  20. Antibiotic resistance in bacterial communities.Current opinion in microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Andrés Aranda-DíazDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-0566-4901
Benjamin ObadiaDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-3286-3236
Ren DodgeDepartment of Embryology, Carnegie Institution of Washington, Baltimore, United States.
Tani ThomsenDepartment of Bioengineering, Stanford University, Stanford, United States.
Zachary F HallbergDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, United States.
Zehra Tüzün GüvenerDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
William B LudingtonDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0001-9637-4493
Kerwyn Casey HuangDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-8043-8138
University of California, Berkeley · USCarnegie Institution for Science · USStanford University · USChan Zuckerberg Initiative (United States) · US

Funding

Engineering of cell shape and intracellular organizationDP2OD006466 · OD · STANFORD UNIVERSITY · PI HUANG, KERWYN C. · 2009 to 2009
$2.4M
Developing a reduced complexity model gut microbiome in the behavior model, Drosophila melanogasterDP5OD017851 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI LUDINGTON, WILLIAM BASIL · 2013 to 2017
$2.0M
National Science Foundation MCB-1149328NIH HHS DP2 OD006466NIH HHS DP5 OD017851
6 · The paper itself

Abstract

Predicting antibiotic efficacy within microbial communities remains highly challenging. Interspecies interactions can impact antibiotic activity through many mechanisms, including alterations to bacterial physiology. Here, we studied synthetic communities constructed from the core members of the fruit fly gut microbiota. Co-culturing of

Indexed as

Hydrogen-Ion ConcentrationAnti-Bacterial AgentsBacteriaDrug Resistance, BacterialMicrobiotaSpecies SpecificityAnti-Bacterial Agentsantibiotic toleranceDrosophila melanogasterecologygut microbiotainfectious diseaseinterspecies interactionsLactobacillus plantarummicrobiologyrifampin

Identifiers

PMID31995029
PMCPMC7025823
OpenAlexW3004043031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.