Evidence map›Paper›PMID 31994821›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2020

Barriers to kidney transplant evaluation in HIV-positive patients with advanced kidney disease: A single-center study.

Suzanne M Boyle, Kallie Fehr, Catylin Deering, Abbas Raza, Meera N Harhay, Gregory Malat, Karthik Ranganna, Dong Heun Lee

Open access · greenAbstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Early steps to kidney transplantation among persons with HIV and end-stage renal disease in ESRD network 6.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Suzanne M BoyleDivision Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.ORCID https://orcid.org/0000-0003-4062-8954
Kallie FehrDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Catylin DeeringDivision of Infectious Disease, Department of Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Abbas RazaDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Meera N HarhayDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Gregory MalatDepartment of Medicine, Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Karthik RangannaDepartment of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Dong Heun LeeDivision of Infectious Disease and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Drexel University · USReading Hospital · USTemple University · USUniversity of Pennsylvania · USUniversity of Toledo · US

Funding

Patterns and Implications of Functional Decline Among Kidney Transplant CandidatesK23DK105207 · NIDDK · DREXEL UNIVERSITY · PI HARHAY, MEERA NAIR · 2015 to 2019
$861k
NIDDK NIH HHS K23 DK105207NIDDK NIH HHS K23DK105207
6 · The paper itself

Abstract

backgroundHIV-positive kidney transplant (KT) recipients have similar outcomes to HIV-negative recipients. However, HIV-positive patients with advanced kidney disease might face additional barriers to initiating the KT evaluation process. We sought to characterize comorbidities, viral control and management, viral resistance, and KT evaluation appointment rates in a cohort of KT evaluation-eligible HIV-positive patients.

methodsWe included patients seen between January 1, 2008, and December 31, 2015, at a primary care HIV clinic who met KT evaluation eligibility by an estimated glomerular filtration rate ≤20 mL/min/1.73 meters

resultsOf 3735 patients evaluated at the HIV primary clinic during the study period, 42 (1.6%) were KT evaluation-eligible patients. The median age was 47 years, 77% were male, and 95%, black. Median CD4 count was 328 cells/mm

conclusionKidney transplant evaluation-eligible HIV-positive patients had a high rate of evaluation appointments, but a low rate of preemptive evaluation appointments. Schizophrenia and viral resistance disproportionally affected patients without evaluation appointments. These data precede the recommendation for universal ART for all HIV+ patients, regardless of CD4 count and viral load, and must be interpreted in the context of this limitation.

Indexed as

Eligibility DeterminationAdultAnti-Retroviral AgentsCD4 Lymphocyte CountElectronic Health RecordsFemaleGlomerular Filtration RateHIV InfectionsHumansKidney DiseasesKidney TransplantationMaleMiddle AgedRetrospective StudiesViral LoadAnti-Retroviral AgentsdisparityHIVkidney transplantkidney transplant evaluation

Identifiers

PMID31994821
PMCPMC7162707
OpenAlexW3003335647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.