Evidence map›Paper›PMID 31994660›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2020

Human platelet antigen-3 polymorphism as a risk factor for rheumatological manifestations in hepatitis C.

Natália Bronzatto Medolago, Adriana Camargo Ferrasi, Oswaldo Melo da Rocha, Maria Inês de Moura Campos Pardini, Rejane Maria Tommasini Grotto, Aline Faria Galvani, Giovanni Faria Silva

Open access · diamondAbstract read
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Natália Bronzatto MedolagoUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.
Adriana Camargo FerrasiUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.ORCID http://orcid.org/0000-0001-9200-5391
Oswaldo Melo da RochaUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.
Maria Inês de Moura Campos PardiniUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.
Rejane Maria Tommasini GrottoUniversidade Estadual Paulista, Departamento de Bioprocessos e Biotecnologia, Faculdade de Ciências Agronômicas, Botucatu, SP, Brasil.
Aline Faria GalvaniUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.
Giovanni Faria SilvaUniversidade Estadual Paulista, Departamento de Clínica Médica, Faculdade de Medicina de Botucatu, Botucatu, SP, Brasil.
Universidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis C virus (HCV) infection is involved in the pathogenesis of autoimmune and rheumatic disorders. Although the human platelet antigens (HPA) polymorphism are associated with HCV persistence, they have not been investigated in rheumatological manifestations (RM). This study focused on verifying associations between allele and genotype HPA and RM in patients with chronic hepatitis C.

methodsPatients (159) with chronic hepatitis C of both genders were analyzed.

resultsWomen showed association between HPA-3 polymorphisms and RM.

conclusionsAn unprecedented strong association between rheumatological manifestations and HPA-3 polymorphism, possibly predisposing women to complications during the disease course, was observed.

Indexed as

AdolescentAdultAgedAged, 80 and overAllelesAntigens, Human PlateletFemaleGenotypeHepatitis C, ChronicHumansMaleMiddle AgedPolymorphism, GeneticRheumatic DiseasesRisk FactorsYoung AdultAntigens, Human Platelet

Identifiers

PMID31994660
PMCPMC7083341
OpenAlexW3004219758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.