Evidence map›Paper›PMID 31994387›Full record

ArticleAnalytical chemistry2020

Flow-Free Microfluidic Device for Quantifying Chemotaxis in Spermatozoa.

Johanna T W Berendsen, Stella A Kruit, Nihan Atak, Ellen Willink, Loes I Segerink

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
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  15. Article
  16. Bioengineering Approaches for Placental Research.Annals of biomedical engineering · 2021
    Review
  17. Article
  18. Role and Modulation of TRPV1 in Mammalian Spermatozoa: An Updated Review.International journal of molecular sciences · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Johanna T W BerendsenBIOS-Lab on a Chip Group, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine , University of Twente , 7500 AE Enschede , The Netherlands.ORCID 0000-0001-6464-3708
Stella A KruitBIOS-Lab on a Chip Group, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine , University of Twente , 7500 AE Enschede , The Netherlands.
Nihan AtakBIOS-Lab on a Chip Group, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine , University of Twente , 7500 AE Enschede , The Netherlands.
Ellen WillinkBIOS-Lab on a Chip Group, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine , University of Twente , 7500 AE Enschede , The Netherlands.
Loes I SegerinkBIOS-Lab on a Chip Group, MESA+ Institute for Nanotechnology and MIRA Institute for Biomedical Technology and Technical Medicine , University of Twente , 7500 AE Enschede , The Netherlands.
University of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current male fertility diagnosis tests focus on assessing the quality of semen samples by studying the concentration, total volume, and motility of spermatozoa. However, other characteristics such as the chemotactic ability of a spermatozoon might influence the chance of fertilization. Here we describe a simple, easy to fabricate and handle, flow-free microfluidic chip to test the chemotactic response of spermatozoa made out of a hybrid hydrogel (8% gelatin/1% agarose). A chemotaxis experiment with 1 μM progesterone was performed that significantly demonstrated that boar spermatozoa are attracted by a progesterone gradient.

Indexed as

ChemotaxisLab-On-A-Chip DevicesAnimalsHydrogelsMaleProgesteroneSpermatozoaSwineHydrogelsProgesterone

Identifiers

PMID31994387
PMCPMC7031847
OpenAlexW3004163986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.