Evidence map›Paper›PMID 31994307›Full record

Observational studyColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2020

Comparison between high-resolution water-perfused anorectal manometry and THD

C A Leo, E Cavazzoni, M M N Leeuwenburgh, G P Thomas, A Dennis, P Bassett, J D Hodgkinson, J Warusavitarne, J Murphy, C J Vaizey

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  4. Observational
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

C A LeoSir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.ORCID 0000-0001-5759-0345
E CavazzoniSanta Maria della Misericordia Hospital, Università degli Studi di Perugia, Perugia, Italy.
M M N LeeuwenburghThe Royal London Hospital, London, UK.
G P ThomasSir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.
A DennisSir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.
P BassettStatsconsultancy Ltd, Amersham, UK.
J D HodgkinsonSir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.
J WarusavitarneSir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.
J MurphyImperial College of London, London, UK.
C J VaizeySir Alan Park's Physiology Unit, St Mark's Hospital Academic Institute, Harrow, UK.
St Mark's Hospital · GBRoyal London Hospital · GBImperial College London · GBUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimAnorectal physiology tests provide a functional assessment of the anal canal. The aim of this study was to compare the results generated by standard high-resolution water-perfused manometry (WPM) with the newer THD

methodThis was a prospective observational study. Conventional manometry was carried out using a water-perfused catheter with high-resolution manometry and compared with the Anopress system with air-filled catheters. All patients underwent the two procedures successively in a randomized order. Time to arrive at the resting pressure plateau, resting, squeeze, straining pressure and visual analogue scale (VAS) scores for pain were recorded. A qualitative analysis of the two devices was performed.

resultsBetween 2016 and 2017, 60 patients were recruited. The time from insertion of the catheter to arriving at the resting pressure plateau was significantly lower with the Anopress compared with WPM: 12 s [interquartile range (IQR) 10-17 s] versus 100 s (IQR 67-121 s) (P < 0.001). A strong correlation between the manometric values of WPM and the Anopress was observed. Both procedures were well tolerated, although the VAS score for insertion of the WPM catheter was significantly higher. The Anopress was easier to use and more time-efficient than the WPM.

conclusionThe pressure values obtained with Anopress correlated well with those of conventional manometry. The Anopress has the advantage of being less time-consuming, user-friendly and better tolerated by patients.

Indexed as

Anus DiseasesFecal IncontinenceAnal CanalCathetersHumansManometryRectumWaterWaterAnopressanorectal manometryanorectal physiology testsfaecal incontinencehigh-resolution manometryphysiologywater-perfused manometry

Identifiers

PMID31994307
PMCPMC7496679
OpenAlexW3004292081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.