Evidence map›Paper›PMID 31993956›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Validation of multiparametric rubidium-82 PET myocardial blood flow quantification for cardiac allograft vasculopathy surveillance.

Sharon Chih, Aun Yeong Chong, Jordan Bernick, George A Wells, Robert A deKemp, Ross A Davies, Ellamae Stadnick, Derek Y So, Christopher Overgaard, Lisa M Mielniczuk and 1 more

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Future of Radionuclide Myocardial Perfusion Imaging: Transitioning from SPECT to PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  2. Apical hypertrophic cardiomyopathy after heart transplantation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sharon ChihDivision of Cardiology, Heart Failure and Transplantation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada. schih@ottawaheart.ca.
Aun Yeong ChongDivision of Cardiology, Interventional Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Jordan BernickDivision of Cardiology, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada.
George A WellsDivision of Cardiology, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Robert A deKempDivision of Cardiology, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Ross A DaviesDivision of Cardiology, Heart Failure and Transplantation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Ellamae StadnickDivision of Cardiology, Heart Failure and Transplantation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Derek Y SoDivision of Cardiology, Interventional Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Christopher OvergaardDivision of Cardiology, Toronto General Hospital-University Health Network, Toronto, Canada.
Lisa M MielniczukDivision of Cardiology, Heart Failure and Transplantation, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON, K1Y 4W7, Canada.
Rob S B BeanlandsCardiac Imaging, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe previously demonstrated high diagnostic accuracy of Rubidium-82 positron emission tomography (PET) myocardial blood flow (MBF) quantification for CAV. The purpose of this study was to validate multiparametric PET detection of CAV by combined rate-pressure-product-corrected myocardial flow reserve (cMFR), stress MBF, and coronary vascular resistance (CVR) assessment. METHODS AND

resultsDiagnostic CAV cut-offs of cMFR < 2.9, stress MBF < 2.3, CVR > 55 determined in a previous study (derivation) were assessed in heart transplant recipients referred for coronary angiography and intravascular ultrasound (IVUS) (validation). CAV was defined as International Society of Heart and Lung Transplantation CAV

conclusionWe validate the diagnostic accuracy of multiparametric PET flow quantification by cMFR, stress MBF, and CVR for CAV.

Indexed as

Myocardial Perfusion ImagingPositron-Emission TomographyAdultAgedAlgorithmsCohort StudiesCoronary AngiographyFemaleFractional Flow Reserve, MyocardialHeart DiseasesHeart TransplantationHumansMaleMiddle AgedReproducibility of ResultsRubidium RadioisotopesRubidium-82Rubidium RadioisotopesCardiac allograft vasculopathyHeart transplantationMyocardial blood flowPET

Identifiers

PMID31993956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.