Evidence map›Paper›PMID 31993949›Full record

SynthesisSports medicine (Auckland, N.Z.)2020

Determining the Sites of Neural Adaptations to Resistance Training: A Systematic Review and Meta-analysis.

Ummatul Siddique, Simin Rahman, Ashlyn K Frazer, Alan J Pearce, Glyn Howatson, Dawson J Kidgell

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 8 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 8 syntheses or guidelines pooled it, 119 citations in OpenAlex.

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  17. Tracking the corticospinal responses to strength training.European journal of applied physiology · 2020
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Ummatul SiddiqueDepartment of Neurology, Institute of Neurosciences, Kolkata, India.
Simin RahmanDepartment of Neurology, Institute of Neurosciences, Kolkata, India.
Ashlyn K FrazerDepartment of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, PO Box 527, Frankston, Melbourne, VIC, 3199, Australia.
Alan J PearceFaculty of Science, Health and Engineering, School of Allied Health, La Trobe University, Melbourne, Australia.
Glyn HowatsonFaculty of Health and Life Sciences, Northumbria University, Newcastle-upon-Tyne, UK.
Dawson J KidgellDepartment of Physiotherapy, School of Primary and Allied Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, PO Box 527, Frankston, Melbourne, VIC, 3199, Australia. dawson.kidgell@monash.edu.ORCID http://orcid.org/0000-0002-2271-1298
Institute of Neurosciences Kolkata · INLa Trobe University · AUMonash Health · AUMonash University · AUNorth-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistance-training causes changes in the central nervous system (CNS); however, the sites of these adaptations remain unclear.

objectiveTo determine sites of neural adaptation to resistance-training by conducting a systematic review and meta-analysis on the cortical and subcortical responses to resistance-training.

methodsEvidence from randomized controlled trials (RCTs) that focused on neural adaptations to resistance-training was pooled to assess effect estimates for changes in strength, cortical, and subcortical adaptations.

resultsThe magnitude of strength gain in 30 RCTs (n = 623) reported a standardised mean difference (SMD) of 0.67 (95% CI 0.41, 0.94; P < 0.001) that measured at least one cortical/subcortical neural adaptation which included: motor-evoked potentials (MEP; 19 studies); silent period (SP; 7 studies); short-interval intracortical inhibition (SICI; 7 studies); cervicomedullary evoked potentials (CMEP; 1 study); transcranial magnetic stimulation voluntary activation (VA

conclusionThere are subtle neural adaptations following resistance-training involving both cortical and subcortical adaptations that act to increase motoneurone activation and likely contribute to the training-related increase in muscle strength.

Indexed as

Adaptation, PhysiologicalEvoked Potentials, MotorResistance TrainingElectromyographyHumansMuscle, SkeletalMuscle StrengthTranscranial Magnetic Stimulation

Identifiers

PMID31993949
OpenAlexW3003203428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.