Evidence map›Paper›PMID 31993695›Full record

ArticlePsychopharmacology2020

Heroin choice depends on income level and economy type.

Tommy Gunawan, Yosuke Hachiga, Christopher S Tripoli, Alan Silberberg, David N Kearns

Open access · greenAbstract read
In one paragraph

Article in Psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Tommy GunawanPsychology Department, American University, 4400 Massachusetts Ave NW, Washington, DC, 20016, USA.
Yosuke HachigaCenter for Decision Research, Waseda University, Tokyo, Japan.
Christopher S TripoliPsychology Department, American University, 4400 Massachusetts Ave NW, Washington, DC, 20016, USA.
Alan SilberbergPsychology Department, American University, 4400 Massachusetts Ave NW, Washington, DC, 20016, USA.
David N KearnsPsychology Department, American University, 4400 Massachusetts Ave NW, Washington, DC, 20016, USA. kearns@american.edu.ORCID http://orcid.org/0000-0002-1759-6723
American University · USWaseda University · JP

Funding

Addiction as Maladaptive Choice of Drugs over Non-Drug RewardsR01DA037269 · NIDA · AMERICAN UNIVERSITY · PI KEARNS, DAVID N · 2015 to 2019
$1.6M
Japan Society for the Promotion of Science 0845NIDA NIH HHS DA037269NIDA NIH HHS R01 DA037269
6 · The paper itself

Abstract

rationaleIn a previous study, investigating choice between heroin and a non-drug alternative in animals and reductions in income (i.e., choices/day) caused the percentage of income spent on heroin to progressively decrease. In contrast, another study found that humans with opioid use disorder spent the majority of their income on heroin even though they had little income. Comparison of these two studies suggests that the seemingly conflicting results could be explained by differences in the underlying economy types of the choice alternatives.

objectiveThe present experiment tested the hypothesis that the effect of income changes on choice between heroin and a non-drug alternative depends on economy type.

methodsRats chose between heroin and saccharin under three income levels. For the Closed group, the choice session was the only opportunity to obtain these reinforcers. For the Heroin Open group and the Saccharin Open group, choice sessions were followed by 3-h periods of unlimited access to heroin or saccharin, respectively.

resultsAs income decreased, the Closed and Heroin Open groups, but not the Saccharin Open group, spent an increasingly greater percentage of income on saccharin than on heroin. The Saccharin Open group, compared to the other groups, spent a greater percentage of income on heroin as income decreased.

conclusionsResults confirm that the effects of income and economy type can interact and this may explain the apparently discrepant results of earlier studies. More generally, findings suggest that situations where heroin choice has little consequence for consumption of non-drug alternatives may promote heroin use.

Indexed as

Analgesics, OpioidAnimalsBehavior, AddictiveChoice BehaviorHeroinMaleRatsRats, Long-EvansSaccharinSelf AdministrationSweetening AgentsAnalgesics, OpioidHeroinSaccharinSweetening AgentsBehavioral economicsChoiceEconomy typeHeroinIncomeRats

Identifiers

PMID31993695
PMCPMC7196508
OpenAlexW3003951167

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.