Evidence map›Paper›PMID 31993656›Full record

ArticleSocial cognitive and affective neuroscience2019

Neural activity in human ventromedial prefrontal cortex reflecting the intention to save reward.

Leopold Zangemeister, Fabian Grabenhorst, Wolfram Schultz

Open access · goldAbstract read
In one paragraph

Article in Social cognitive and affective neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. The amygdala and the pursuit of future rewards.Frontiers in neuroscience · 2024
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Leopold ZangemeisterDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, U.K.
Fabian GrabenhorstDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, U.K.
Wolfram SchultzDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, U.K.
University of Cambridge · GB

Funding

The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI O'DOHERTY, JOHN P · 2012 to 2021
$18.6M
NIMH NIH HHS P50 MH094258Wellcome Trust 204811/Z/16/ZWellcome Trust 206207/Z/17/ZWellcome Trust WT 095495Wellcome Trust WT 204811
6 · The paper itself

Abstract

Saving behavior usually requires individuals to perform several consecutive choices before collecting the final reward. The overt behavior is preceded by an intention to perform an appropriate choice sequence. We studied saving sequences for which each participant rated the intention numerically as willingness to save. Each sequence resulted in a specific reward amount and thus had a particular value for the participant, which we assessed with a Becker-DeGroot-Marschak auction-like mechanism. Using functional MRI, we found that blood-oxygen-level-dependent signals in human ventromedial prefrontal cortex (vmPFC) correlated with the participant's stated intention before each choice sequence. An adjacent vmPFC region showed graded activation that reflected the value of the sequence. These results demonstrate an involvement of vmPFC in intentional processes preceding sequential economic choices.

Indexed as

IntentionRewardAdultChoice BehaviorFemaleHumansMagnetic Resonance ImagingMalePrefrontal CortexBDMchoicefunctional MRIplanningsequence

Identifiers

PMID31993656
PMCPMC7137725
OpenAlexW3001284891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.