Evidence map›Paper›PMID 31993105›Full record

ArticleInternational journal of physiology, pathophysiology and pharmacology2019

Disseminated cryptococcosis with multiple and mediastinal lymph node enlargement and lung involvement in an immunocompetent child.

Jun Chen, Meng-Jie Zhang, Xu-Hua Ge, Yan-Hua Liu, Tao Jiang, Jun Li, Zhuo Li, Hong-Jun Miao, Jun Yang

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of physiology, pathophysiology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Frontiers in medicine · 2026
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jun ChenDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Meng-Jie ZhangDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Xu-Hua GeDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Yan-Hua LiuDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Tao JiangDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Jun LiDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Zhuo LiDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Hong-Jun MiaoDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Jun YangDepartment of Emergency, Children's Hospital of Nanjing Medical University Guangzhou Road, No. 72, Nanjing, Jiangsu Province, China.
Nanjing Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDisseminated cryptococcosis is less common in individuals with normal immune function. Most cases occur in HIV-infected people. Usually it affects the lungs, followed by the central nervous system (CNS), skin and bone marrow, but rarely to the lymph nodes and chest wall. CASE PRESENTATION: This article reports a case of cryptococcal infection diagnosed as "lymphoma?" in a local hospital. It was characterized by chronic fever, weight loss, neck, axillary and inguinal lymph nodes enlargement, mediastinal and parabronchial lymphadenopathy, multiple nodular high-density images of both lungs, multi-serosal effusion, liver enlargement and other presentations.

conclusionsDisseminated cryptococcosis can occur in immunocompromised children without HIV infection. This case of multiple and mediastinal lymphadenopathy, easily misdiagnosed as "lymphoma", requires high clinical suspicion and early initiation of treatment to effectively identify and treat patients.

Indexed as

childDisseminated cryptococcosismultiple lymphadenopathy

Identifiers

PMID31993105
PMCPMC6971505
OpenAlexW3004379685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.