Evidence map›Paper›PMID 31993104›Full record

ArticleInternational journal of physiology, pathophysiology and pharmacology2019

Comparing urine levels of BLCA-4 nuclear matrix protein in patients with bladder cancer and non-bladder cancer.

Ali Alavi, Mohammad-Hosein Izadpanahi, Leila Haghshenas, Romina Faridizad, Mohammad-Javad Eslami, Keyvan Ghadimi

Open access · greenAbstract read
In one paragraph

Article in International journal of physiology, pathophysiology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Evaluation of glomerular filtration rate decline in patients with renal colic.American journal of clinical and experimental urology · 2022
    Article
  7. Article
  8. Biomarkers in Bladder Cancer Surveillance.Frontiers in surgery · 2021
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ali AlaviDepartment of Research, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Mohammad-Hosein IzadpanahiDepartment of Urology, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Leila HaghshenasDepartment of Molecular and Cellular Biology, International University of Spain Spain.
Romina FaridizadDepartment of Research, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Mohammad-Javad EslamiDepartment of Research, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Keyvan GhadimiDepartment of Research, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe molecular mechanism of bladder cancer is yet not fully understood. Aim of this study was to compare the levels of BLCA-4 nuclear matrix protein in the urine of patients with bladder cancer and non-affected individuals. MATERIALS AND

methodThe current cross sectional study was conducted on 45 patients with bladder cancer and 45 patients without bladder cancer who were referred to Alzahra Hospital of Isfahan, Iran in 2017. BCLA-4 Urinary Marker was measured in urine of the patients and individuals. Also correlation between the urine levels of BCLA-4 and other variables were evaluated.

resultsThe urine levels of BLCA-4 in the patients with bladder cancer was significantly higher than non-bladder cancer group (P<0.001). There was no significant relationship between urine levels of BLCA-4 with tumor stage and size (P>0.05).

conclusionThe present study indicated that high urine levels of BLCA-4 was presented in patients with bladder cancer and this tumor marker has a high capability for early diagnosis of the disease, which can be used for screening and follow-up of bladder cancer.

Indexed as

bladderBLCA-4malignancyurine

Identifiers

PMID31993104
PMCPMC6971499
OpenAlexW3003178805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.