Evidence map›Paper›PMID 31993099›Full record

ReviewInternational journal of physiology, pathophysiology and pharmacology2019

Mechanism of membrane fusion: protein-protein interaction and beyond.

Hongbing Wang, Chengliang Zhang, Hua Xiao

Open access · greenAbstract readReview
In one paragraph

Review in International journal of physiology, pathophysiology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Golgi inCOGnito: From vesicle tethering to human disease.Biochimica et biophysica acta. General subjects · 2020
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hongbing WangDepartment of Physiology, Michigan State University East Lansing, Michigan 48824, USA.
Chengliang ZhangDepartment of Physiology, Michigan State University East Lansing, Michigan 48824, USA.
Hua XiaoDepartment of Physiology, Michigan State University East Lansing, Michigan 48824, USA.
Michigan State University · US

Funding

Nonconventional role of ADCY in Gq-mediated neuronal signaling and neuroplasticityR01MH119149 · NIMH · MICHIGAN STATE UNIVERSITY · PI WANG, HONGBING · 2019 to 2023
$2.3M
Role of NCOA5 in hepatic steatosis and hepatocarcinogenesisR01CA188305 · NCI · MICHIGAN STATE UNIVERSITY · PI XIAO, HUA · 2015 to 2019
$1.7M
NCI NIH HHS R01 CA188305NIMH NIH HHS R01 MH119149
6 · The paper itself

Abstract

Membrane fusion is a universal event in all living organism. It is at the heart of intracellular organelle biogenesis and membrane traffic processes such as endocytosis and exocytosis, and is also used by enveloped viruses to enter hosting cells. Regarding the cellular mechanisms underlying membrane fusion, pioneering studies by Randy Schekman, James Rothman, Thomas C. Südhof and their colleagues have demonstrated the function of specific proteins and protein-protein interactions as essential fusogenic factor to initiate membrane fusion. Since then, function of lipids and protein-lipid interaction has also been identified as important players in membrane fusion. Based on that NSF (NEM-sensitive factor where NEM stands for

Indexed as

ACSL4Acyl-CoAEndo B1endosomelysosomemembrane fusionNSFphosphatidic acidRab5aSNARETip30

Identifiers

PMID31993099
PMCPMC6971501
OpenAlexW3006514523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.