Evidence map›Paper›PMID 31993055›Full record

ArticleFrontiers in immunology2019

Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation.

Oliver H Bell, David A Copland, Amy Ward, Lindsay B Nicholson, Clemens A K Lange, Colin J Chu, Andrew D Dick

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  4. Comparative models of uveitis.Eye (London, England) · 2025
    Review
  5. Characterization of the ocular inflammatory response to AAV reveals divergence by sex and age.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Oliver H BellAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
David A CoplandAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Amy WardAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Lindsay B NicholsonAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Clemens A K LangeEye Clinic, Medical Centre, University of Freiburg, Freiburg, Germany.
Colin J ChuAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
Andrew D DickAcademic Unit of Ophthalmology, Translational Health Sciences, University of Bristol, Bristol, United Kingdom.
University of Bristol · GBUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell DifferentiationEndotoxinsInflammationLipopolysaccharidesMaleMiceMice, Inbred C57BLMicrogliaNeurogliaReceptor, Anaphylatoxin C5aRetinaRNA, MessengerSignal TransductionTranscriptomeUveitisEndotoxinsLipopolysaccharidesReceptor, Anaphylatoxin C5aRNA, Messengerheterogeneitylipopolysaccharide (LPS)microgliamRNA-Seqresolutionretinatranscriptomeuveitis

Identifiers

PMID31993055
PMCPMC6964706
OpenAlexW2999700096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.