Evidence map›Paper›PMID 31993024›Full record

ArticleFrontiers in microbiology2019

Comparing Cathelicidin Susceptibility of the Meningitis Pathogens

Marita Meurer, Nicole de Buhr, Linn Meret Unger, Marta C Bonilla, Jana Seele, Roland Nau, Christoph G Baums, Thomas Gutsmann, Stefan Schwarz, Maren von Köckritz-Blickwede

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. d-Alanylation of Lipoteichoic Acids inFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Marita MeurerDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Foundation, Hanover, Germany.
Nicole de BuhrDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Foundation, Hanover, Germany.
Linn Meret UngerDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Foundation, Hanover, Germany.
Marta C BonillaDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Foundation, Hanover, Germany.
Jana SeeleDepartment of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany.
Roland NauDepartment of Neuropathology, University Medical Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany.
Christoph G BaumsInstitute of Bacteriology and Mycology, Center for Infectious Diseases, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
Thomas GutsmannResearch Group Biophysics, Research Center Borstel, Borstel, Germany.
Stefan SchwarzDepartment of Veterinary Medicine, Institute of Microbiology and Epizootics, Center for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Maren von Köckritz-BlickwedeDepartment of Physiological Chemistry, University of Veterinary Medicine Hannover, Foundation, Hanover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEEvangelisches Krankenhaus Göttingen-Weende · DEFreie Universität Berlin · DELeipzig University · DEResearch Center Borstel - Leibniz Lung Center · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host defense peptides or antimicrobial peptides (AMPs), e.g., cathelicidins, have recently been discussed as a potential new treatment option against bacterial infections. To test the efficacy of AMPs, standardized methods that closely mimic the physiological conditions at the site of infection are still needed. The aim of our study was to test the meningitis-causing bacteria

Indexed as

AMPcerebrospinal fluid (CSF)Escherichia coliLL-37MICPR-39Streptococcus suis

Identifiers

PMID31993024
PMCPMC6971174
OpenAlexW2999313228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.