Evidence map›Paper›PMID 31992985›Full record

ArticleFrontiers in pharmacology2019

Pulmonary Toxicity and the Pathophysiology of Electronic Cigarette, or Vaping Product, Use Associated Lung Injury.

Hitendra S Chand, Thivanka Muthumalage, Wasim Maziak, Irfan Rahman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Identifying Adolescent Vaping With Screening to Brief Intervention and Brief Screener for Tobacco, Alcohol, and Drugs Screening Tools.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Trial
  3. Review
  4. Self-reported voice symptoms in e-cigarette users: a cross-sectional study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  5. Article
  6. Review
  7. Vaping: Public Health, Social Media, and Toxicity.Online journal of public health informatics · 2024
    Article
  8. Vaping-Dependent Pulmonary Inflammation Is CaInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hitendra S ChandDepartment of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.
Thivanka MuthumalageDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States.
Wasim MaziakDepartment of Epidemiology, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL, United States.
Irfan RahmanDepartment of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, United States.
Florida International University · USUniversity of Rochester Medical Center · US

Funding

WNY Center for Research on Flavored Tobacco Products (CRoFT)U54CA228110 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI GONIEWICZ, MACIEJ LUKASZ · 2018 to 2022
$19.8M
Inflammatory and Dysregulated Repair Responses to Inhaled NicotineR01HL135613 · NHLBI · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN · 2017 to 2021
$2.7M
Translating evidence and building capacity to support waterpipe control in the Eastern MediterraneanR01TW010654 · FIC · FLORIDA INTERNATIONAL UNIVERSITY · PI ASFAR, TAGHRID, MAZIAK, WASIM · 2017 to 2021
$1.8M
Understanding tobacco flavor effects on waterpipe smokers’ experiences and exposuresR01DA042477 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI MAZIAK, WASIM · 2016 to 2018
$1.3M
Novel long noncoding RNAs in the airway mucous responseR21AI144374 · NIAID · FLORIDA INTERNATIONAL UNIVERSITY · PI LAKSHMANA, MADEPALLI KRISHNAPPA · 2019 to 2020
$625k
FIC NIH HHS R01 TW010654NCI NIH HHS U54 CA228110NHLBI NIH HHS R01 HL135613NIAID NIH HHS R21 AI144374NIDA NIH HHS R01 DA042477
6 · The paper itself

Abstract

New emerging tobacco products, especially electronic cigarettes (E-Cig) or electronic nicotine delivery systems (ENDS), have gained a huge popularity, particularly in younger populations. The lack of sufficient evidence-based health effect studies has promoted widespread use/abuse with the assumption that E-Cig or ENDS and/or vaping products are safer and less toxic than conventional tobacco smoking. However, the recent escalation in acute lung injuries and their associated fatalities among ENDS or vaping product users has now brought attention to this silent epidemic

Indexed as

E-cigarettesEVALIlipoid pneumoniatetrahydrocannabinol (THC)vaping

Identifiers

PMID31992985
PMCPMC6971159
OpenAlexW2999214627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.