Evidence map›Paper›PMID 31992976›Full record

ArticleFrontiers in behavioral neuroscience2019

Dopamine D

Giordano de Guglielmo, Marsida Kallupi, Sharona Sedighim, Amy H Newman, Olivier George

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 47 citations in OpenAlex.

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  14. Effects of selective dopamine D3 receptor partial agonist/antagonists on oxycodone self-administration and antinociception in monkeys.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giordano de GuglielmoDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Marsida KallupiDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Sharona SedighimDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Amy H NewmanMolecular Targets and Medications Discovery Branch, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, United States.
Olivier GeorgeDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
University of California, San Diego · USNational Institute on Drug Abuse · US

Funding

Use of Next-Gen Sequencing to Identify Genetic Variants that Influence compulsiveOxycodone Intake in Outbred RatsU01DA044451 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Olivier George, Abraham A Palmer · 2018 to 2026
$7.3M
NIDA NIH HHS U01 DA044451
6 · The paper itself

Abstract

Prescription opioids, such as oxycodone, are highly effective analgesics for clinical pain management, but approximately 25% of patients who are prescribed opioids misuse them, and 5%-10% develop an opioid use disorder (OUD). Effective therapies for the prevention and treatment of opioid abuse and addiction need to be developed. The present study evaluated the effects of the highly selective dopamine D

Indexed as

dependanceescalationopioidVK4-116withdrawal

Identifiers

PMID31992976
PMCPMC6971096
OpenAlexW2999165469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.