Evidence map›Paper›PMID 31992942›Full record

ArticleJournal of clinical orthopaedics and trauma2020

Repeat irrigation & debridement for patients with acute septic knee arthritis: Incidence and risk factors.

Seth Stake, Ryan Scully, Samuel Swenson, Danny Lee, Ryan Lee, Andrew Sparks, Rajeev Pandarinath

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical orthopaedics and trauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Susceptibility ofMolecules (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Associations with unplanned repeat irrigation and debridement of native septic arthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Seth StakeThe George Washington University Hospital Department of Orthopaedic Surgery, 2300 M St NW, Washington, DC, 20037, USA.
Ryan ScullyThe George Washington University Hospital Department of Orthopaedic Surgery, 2300 M St NW, Washington, DC, 20037, USA.
Samuel SwensonThe George Washington University Hospital Department of Orthopaedic Surgery, 2300 M St NW, Washington, DC, 20037, USA.
Danny LeeThe George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Ryan LeeThe George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Andrew SparksThe George Washington University Hospital Department of Orthopaedic Surgery, 2300 M St NW, Washington, DC, 20037, USA.
Rajeev PandarinathThe George Washington University Hospital Department of Orthopaedic Surgery, 2300 M St NW, Washington, DC, 20037, USA.
George Washington University Hospital · USGeorge Washington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeptic knee arthritis is considered an orthopedic emergency due to its significant morbidity and potential to be life-threatening. One important outcome in treatment of septic knee arthritis is whether return to the operating room for repeat irrigation and debridement is required. This complication presents extra burden to the patient, as well as to the health care system. This study aims to first isolate the incidence of repeat irrigation and debridement at the authors' home institution and then define risk factors for repeat washout for septic arthritis of the knee.

methodsRecords from all patients at a single academic institution with acute septic knee arthritis who had arthroscopic or open I&D of the knee joint from January 2005-December 2015 were collected retrospectively. Patients were initially identified on the basis of diagnosis coding in the institution's medical information system. Following collection/screening based on strict inclusion/exclusion criteria, a cohort of 63 patients was ultimately included. 18 patients were assigned to a "repeat washout" (RW) cohort and 45 patients were assigned to a "no repeat washout" (NRW) cohort. Univariate analyses and multivariable regression models were performed between the two washout cohorts to identify variables associated with repeat washout.

resultsPatients requiring a repeat washout (RW) had a statistically significant association with African American/Hispanic race, higher BUN levels, higher serum white blood cell (WBC) count on admission, concurrent infection, and isolated bacteremia when compared to those patients who did not require a repeat washout (NRW) (all respective

conclusionThis study retrospectively isolated risk factors associated with repeat surgical lavage. In the multivariable regression analysis, both concurrent infection and increased synovial WBC count were significantly associated with the need for repeat knee I&D. This finding is significant, as it may signify a potential for increased infectious resilience for acute septic arthritis of the knee secondary to seeding from systemic infection, thus requiring multiple I&Ds to meet resolution. This finding may carry clinical significance in the early stages of patient counseling regarding hospital course and prognosis. LEVEL OF EVIDENCE: IV.

Indexed as

KneeRisk factorsSeptic arthritisWhite blood cell count

Identifiers

PMID31992942
PMCPMC6978190
OpenAlexW2996598639

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.