ArticleJournal of clinical orthopaedics and trauma2020
The future of the amputees with osseointegration: A systematic review of literature.
Article in Journal of clinical orthopaedics and trauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06310239 (Osseointegrated Limb Implant Microbiome Population Adaptation Study), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Osseointegrated Limb Implant Microbiome Population Adaptation Study
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Clinical Outcomes of Bone-Anchored Versus Socket-Suspended Prostheses in Individuals With Transfemoral Amputation: A Systematic Review and Meta-Analysis of Two-Arm Comparative Studies.Orthopaedic surgery · 2026Pooled it
- Analyzing research trends and developments in osseointegration in patients with extremity amputations: Systematic bibliometric analysis and research recommendations.Prosthetics and orthotics international · 2025Pooled it
- Comparison of Quality of Life in Transfemoral Amputee Using Bone-Anchored Prostheses vs. Socket Prostheses: A Systemic Review and Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Percutaneous exposure for tibia osseointegration: reduced antibiotics, improved perioperative metrics, and greater pain reduction versus open exposure.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Wearing Time, Quality of Life, and Complications of Lower Limb Bone-anchored Prostheses: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Altered cumulative joint moments and increased joint moment symmetry during sit-to-stand transitions for transfemoral bone-anchored limb users: A case series.Clinical biomechanics (Bristol, Avon) · 2025Article
- Improved primary stability and load transfer of a customized osseointegrated transfemoral prosthesis compared to a commercial one.Journal of orthopaedic surgery and research · 2025Article
- Somatosensory restoration and neural control strategies in lower-limb prostheses.npj biomedical innovations · 2025Review
- Comparison In Vitro Study on the Interface between Skin and Bone Cell Cultures and Microporous Titanium Samples Manufactured with 3D Printing Technology Versus Sintered Samples.Nanomaterials (Basel, Switzerland) · 2024Article
- Bone mineral density in osseointegration implant surgery: A review of current studies (Review).Biomedical reports · 2024Review
- Emerging Medical Technologies and Their Use in Bionic Repair and Human Augmentation.Bioengineering (Basel, Switzerland) · 2024Review
- Extended physiological proprioception is affected by transhumeral Socket-Suspended prosthesis use.Journal of biomechanics · 2024Article
- Development of an evidence-based diagnostic algorithm for infection in patients with transcutaneous osseointegration following amputation.Journal of bone and joint infection · 2024Article
- ReliableFrontiers in bioengineering and biotechnology · 2024Article
- Osseointegrated prostheses for the rehabilitation of patients with transfemoral amputations: A prospective ten-year cohort study of patient-reported outcomes and complications.Journal of orthopaedic translation · 2023Article
- Review
- Osseointegration Following Transfemoral Amputation After Infected Total Knee Replacement: A Case Series of 10 Patients With a Mean Follow-up of 5 Years.Arthroplasty today · 2022Article
- Finite Element Analysis of Transhumeral and Transtibial Percutaneous Osseointegrated Endoprosthesis Implantation.Frontiers in rehabilitation sciences · 2021Article
- Protecting the skin-implant interface with transcutaneous silver-coated skin-and-bone-integrated pylon in pig and rabbit dorsum models.Journal of biomedical materials research. Part B, Applied biomaterials · 2021Article
- Cortical and medullary morphology of the tibia.Anatomical record (Hoboken, N.J. : 2007) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSocket prosthesis attachment is the current gold standard for limb amputees. Osseointegrated implantation is a novel technique that has many proposed advantages over the current gold standard. Clear advantages for its use over socket prosthetic attachment has been well established in literature. It decreases socket problems as pinching, pressure points, chronic skin problems and frequent socket change due to atrophy of muscles.
methodsWe reviewed primary research articles documenting complication rates and outcome measures in patients with osseointegrated prosthesis implantation after limb amputation.
resultsNine studies were identified with a total of 211-242 patients. Clinical, radiographic, and functional outcomes, as well as complications were considered. The mean duration of follow-up was greater than 12 months in all studies.
conclusionsOsseointegration is an effective alternative to socket prosthesis in transfemoral amputees. Transtibial and upper extremity implants are underreported in the literature and clear indication for their effectiveness over socket prosthesis does not exist. Minor complications are most common, such as soft tissue infections, and may be mitigated in the future by improvements in surgical technique and implant design.The level of evidence is 3.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.