Evidence map›Paper›PMID 31992740›Full record

ArticleScientific reports2020

Risk of active tuberculosis development in contacts exposed to infectious tuberculosis in congregate settings in Korea.

Shin Young Park, Sunmi Han, Young-Man Kim, Jieun Kim, Sodam Lee, Jiyeon Yang, Un-Na Kim, Mi-Sun Park

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Factors Associated With Discontinuation of Tuberculosis Preventive Treatment: Post Hoc Analysis of 2 Randomized, Controlled Trials.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Trial
  2. Body Mass Index and Incident Tuberculosis in Close Tuberculosis Contacts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shin Young ParkDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Sunmi HanDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Young-Man KimDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Jieun KimDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Sodam LeeDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Jiyeon YangDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea.
Un-Na KimDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea. unnakim@korea.kr.
Mi-Sun ParkDivision of TB Investigation, Korea Centers for Disease Control and Prevention, Osong, Republic of Korea. pmsun4686@naver.com.
Korea Center for Disease Control and Prevention · KRKorea Disease Control and Prevention Agency · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contact investigation is an important and effective active case-finding strategy, but there is a lack of research on congregate settings in countries with an intermediate incidence. This study determined the incidence of and risk factors for tuberculosis (TB) development after exposure in congregate settings. This retrospective cohort study included 116,742 contacts identified during the investigation of 2,609 TB cases diagnosed from January to December 2015. We searched the Korean National Tuberculosis Surveillance System TB registry to identify contacts that developed active TB during follow-up until May 2018. During the mean observation period of 2.9 years, 499 of 116,742 contacts (0.4%) developed new active TB. From these contacts, 404 (81.0%) developed TB within 2 years after exposure. The 2-year Kaplan-Meier cumulative risk for TB was the highest in contacts aged ≥65 years [1%; 95% confidence interval (CI), 0.8-1.3]. Contacts with LTBI who completed chemoprophylaxis exhibited a lower risk of active TB development than those without chemoprophylaxis (adjusted hazard ratio, 0.16; 95% CI, 0.08-0.29). Aggressive contact investigation is effective for the early detection and prevention of TB in congregate settings. The risk of progression to active TB among contacts with LTBI can be minimised by the completion of chemoprophylaxis.

Indexed as

AdolescentAdultAgedChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMaleMiddle AgedOdds RatioPopulation SurveillanceProportional Hazards ModelsRepublic of Korea

Identifiers

PMID31992740
PMCPMC6987175
OpenAlexW3004159222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.