Evidence map›Paper›PMID 31992659›Full record

ArticleTobacco control2020

PhenX: Host: Biobehavioral measures for tobacco regulatory research.

Gary A Giovino, Gary E Swan, Ben Blount, Stephanie O'Malley, Darigg C Brown, Tabitha P Hendershot, PhenX TRR Host: Biobehavioral Working Group

Open access · bronzeAbstract read
In one paragraph

Article in Tobacco control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gary A GiovinoDepartment of Health Behavior, University at Buffalo; SUNY, Buffalo, New York, USA ggiovino@buffalo.edu.
Gary E SwanStanford Prevention Research Center, Stanford University School of Medicine, Stanford, California, USA.
Ben BlountTobacco and Volatiles Branch, Division of Laboratory Sciences, CDC, Atlanta, Georgia, USA.
Stephanie O'MalleyPsychiatry, Yale University, New Haven, Connecticut, USA.
Darigg C BrownRTI International, Research Triangle Park, North Carolina, USA.
Tabitha P HendershotRTI International, Research Triangle Park, North Carolina, USA.
PhenX TRR Host: Biobehavioral Working Group
RTI International · USStanford University · USYale University · US

Funding

Genomic Resource Grant for the PhenX Toolkit - expansion and sustainabilityPhenX Supplement for COVID-19 ResearchU41HG007050 · NHGRI · RESEARCH TRIANGLE INSTITUTE · PI HAMILTON, CAROL MARIE · 2013 to 2022
$21.2M
NHGRI NIH HHS U41 HG007050
6 · The paper itself

Abstract

A working group (WG) of experts from diverse fields related to nicotine and tobacco addiction was constituted to identify constructs and measures for the PhenX (Phenotypes and eXposures) Tobacco Regulatory Research (TRR) Host: Biobehavioral Collection with potential relevance to users of both conventional and newer tobacco products. This paper describes the methods and results the WG used to identify, select, approve and place measures in the PhenX TRR Collection. The WG recognised 13 constructs of importance to guide their categorisation of measures already in the PhenX Toolkit ('complementary measures') and to identify novel or improved measures of special relevance to tobacco regulatory science. In addition to the 22 complementary measures of relevance to tobacco use already in the PhenX Toolkit, the WG identified and recommended nine additional Host: Biobehavioral measures characterising the use, exposure and health outcomes of tobacco products for application to TRR. Of these, five were self-administered or interviewer-administered measures: amount, type and frequency of recent tobacco use; flavor preference in e-cigarette users (adult and youth); pregnancy status and tobacco use; pregnancy status-mother and baby health and withdrawal from tobacco use. The remaining four measures were laboratory-based: cotinine in serum, expired carbon monoxide, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine and cue reactivity. Although a number of validated tools are now available in the Host: Biobehavioral Collection, several gaps were identified, including a need to develop and test the identified measures in adolescent samples and to develop or identify measures of nicotine dependence, tolerance and withdrawal associated with newer non-combusted tobacco products.

Indexed as

AdolescentAdultAdvisory CommitteesCarbon DioxideConsensusCotinineCuesData CollectionFemaleHumansMaleNitrosaminesPhenotypePregnancyResearch DesignSmokers4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-olCarbon DioxideCotinineNitrosaminesaddictionbiobheavioralcotinineflavourpregnancysmoking topography

Identifiers

PMID31992659
PMCPMC8127015
OpenAlexW3003934263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.