Evidence map›Paper›PMID 31992650›Full record

ArticleLife science alliance2020

Oxidised metabolites of the omega-6 fatty acid linoleic acid activate dFOXO.

So Yeon Kwon, Karen Massey, Mark A Watson, Tayab Hussain, Giacomo Volpe, Christopher D Buckley, Anna Nicolaou, Paul Badenhorst

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

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  14. Review
  15. Linoleic acid and the regulation of glucose homeostasis: A review of the evidence.Prostaglandins, leukotrienes, and essential fatty acids · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

So Yeon KwonInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, UK.ORCID https://orcid.org/0000-0002-8490-9101
Karen MasseyBradford School of Pharmacy, University of Bradford, Bradford, UK.
Mark A WatsonInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, UK.ORCID https://orcid.org/0000-0002-5423-4457
Tayab HussainInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, UK.
Giacomo VolpeInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, UK.ORCID https://orcid.org/0000-0001-5000-6951
Christopher D BuckleyInstitute of Inflammation and Ageing, Centre for Translational Inflammation Research, Queen Elizabeth Hospital, Edgbaston, UK.ORCID http://orcid.org/0000-0001-6924-6402
Anna NicolaouBradford School of Pharmacy, University of Bradford, Bradford, UK.ORCID https://orcid.org/0000-0002-1314-413X
Paul BadenhorstInstitute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, UK p.w.badenhorst@bham.ac.uk.ORCID https://orcid.org/0000-0002-2542-0250
University of Birmingham · GBUniversity of Bradford · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity-induced inflammation, or meta-inflammation, plays key roles in metabolic syndrome and is a significant risk factor in diabetes and cardiovascular disease. To investigate causal links between obesity, meta-inflammation, and insulin signaling we established a

Indexed as

AnimalsAnimals, Genetically ModifiedCell NucleusChromatinDietary FatsDisease Models, AnimalDrosophilaDrosophila ProteinsFatty Acids, Omega-3Forkhead Box Protein O3Forkhead Transcription FactorsGene Expression RegulationHeLa CellsHumansInflammationInsulin9-hydroxy-10,12-octadecadienoic acidChromatinDietary FatsDrosophila ProteinsFatty Acids, Omega-3Forkhead Box Protein O3Forkhead Transcription FactorsFOXO3 protein, humanFOXO protein, DrosophilaInsulinLinoleic AcidLinoleic Acids, Conjugated

Identifiers

PMID31992650
PMCPMC6988086
OpenAlexW2999904429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.