Evidence map›Paper›PMID 31992621›Full record

ArticlemBio2020

MicroRNA-889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK.

Der-Yuan Chen, Yi-Ming Chen, Chin-Fu Lin, Che-Min Lo, Hung-Jen Liu, Tsai-Ling Liao

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Epigenetic Mechanisms Induced byInternational journal of molecular sciences · 2024
    Review
  9. Article
  10. Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Review
  11. Functional Analysis of Genes inIndian journal of microbiology · 2024
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Different modalities of host cell death and their impact onAmerican journal of physiology. Cell physiology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Der-Yuan ChenDepartment of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Yi-Ming ChenDepartment of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Chin-Fu LinDepartment of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Che-Min LoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Hung-Jen LiuRong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan.ORCID 0000-0002-1460-1494
Tsai-Ling LiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan tlliao@vghtc.gov.tw.ORCID 0000-0001-7059-4228
National Chung Hsing University · TWTaichung Veterans General Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy plays an important role in protecting the host against pathogens.

Indexed as

AutophagyRNA InterferenceBiomarkersCytokine TWEAKGene Expression RegulationHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsHumansLatent TuberculosisMicrobial ViabilityMicroRNAsModels, BiologicalMycobacterium tuberculosisPhagocytosisBiomarkersCytokine TWEAKMicroRNAsTNFSF12 protein, humanautophagybiomarkerlatent tuberculosis infection (LTBI)microRNA-889tumor necrosis factor-like weak inducer of apoptosis (TWEAK)

Identifiers

PMID31992621
PMCPMC6989109
OpenAlexW3004121615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.