Evidence map›Paper›PMID 31992558›Full record

ArticleCMAJ open

Impact of updated recommendations on acetylsalicylic acid use for primary prevention of cardiovascular disease in Canada: a population-based survey.

Myriam Khalili, Fanny Lepeytre, Jason Robert Guertin, Rémi Goupil, Stéphan Troyanov, Josée Bouchard, François Madore

Abstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myriam KhaliliFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
Fanny LepeytreFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
Jason Robert GuertinFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
Rémi GoupilFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
Stéphan TroyanovFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
Josée BouchardFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que.
François MadoreFaculty of Medicine (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Université de Montréal; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (Khalili, Lepeytre, Goupil, Troyanov, Bouchard, Madore), Montréal, Que.; Département de médecine sociale et preventive (Guertin), Faculty of Medicine, Université Laval; Centre de recherche du Centre hospitalier universitaire de Québec (Guertin), Québec, Que. f.madore@umontreal.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe debate over acetylsalicylic acid (ASA) therapy for primary prevention of cardiovascular disease (CVD) has recently resurfaced, but scarce data are available on prophylactic ASA use in Canada for this purpose. This study aimed to evaluate the prevalence and factors associated with ASA use, and the potential impact of implementing the most recent (2016) US Preventive Services Task Force recommendations for primary CVD prevention in a Canadian setting.

methodsWe performed a cross-sectional analysis using data from the CARTaGENE study, which included a representative sample (

resultsA total of 6231 respondents in the CARTaGENE study (54.2% of those aged 50-69 yr with no prior history of CVD) were found to be potentially eligible for ASA use for primary CVD prevention. Of the 6231, 1379 (22.1%) were receiving prophylactic ASA treatment. Factors found to be related to ASA use included age, male sex, regular medical visits, lower education level, obesity, hypertension, diabetes and dyslipidemia. Income and smoking status were not found to be significantly associated with ASA use. Our results indicate that 885 261 people would potentially have started ASA treatment if the US Preventive Services Task Force recommendations had been implemented in Quebec in 2018.

interpretationPrevalent ASA use for primary CVD prevention was low. Implementation of the 2016 US Preventive Services Task Force recommendations would require initiating ASA treatment in a substantial proportion of people, with undetermined potential benefits.

Indexed as

ChemopreventionPrimary PreventionAdultAgedAspirinCanadaCardiovascular DiseasesComorbidityCross-Sectional StudiesFemaleHealth Impact AssessmentHumansMaleMiddle AgedOdds RatioPopulation SurveillanceAspirin

Identifiers

PMID31992558
PMCPMC6996036

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.